Literature DB >> 17147949

[Cochrane reviews compared with industry-supported and other meta-analyses of the same drugs--secondary publication].

Anders W Jørgensen1, Jørgen Hilden, Peter C Gøtzsche.   

Abstract

24 Cochrane reviews were compared with other, closely matched, meta-analyses of the same drugs. The quality score was highest for Cochrane reviews (7 vs. 2, p < 0.01). Of 8 industry-supported reviews, 7 with conclusions all recommended the experimental drug without reservations, compared with none of the Cochrane reviews (p = 0.02) although the estimated treatment effect was similar on average (p = 0.64). Industry-supported reviews were less transparent, had few reservations about methodological limitations of the included trials, and should be read with caution.

Year:  2006        PMID: 17147949

Source DB:  PubMed          Journal:  Ugeskr Laeger        ISSN: 0041-5782


  1 in total

1.  What is the impact of financial conflicts of interest on the development of psychiatry?

Authors:  Andrés Heerlein
Journal:  World Psychiatry       Date:  2007-02       Impact factor: 49.548

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.