Literature DB >> 1714724

Elevated levels of c-jun and c-fos transcripts in the aged rat liver.

T Fujita1, N Maruyama.   

Abstract

Age-associated increases of transcript levels of several genes were studied using aged rat liver. Northern hybridization showed marked increases of c-jun, c-fos, and glutathione S-transferase P (GST-P) in 24-month-old rats. These genes have the 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-responsive element called TRE in their structures. Thus, TRE seems to be involved in important age-associated changes of gene expression.

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Year:  1991        PMID: 1714724     DOI: 10.1016/0006-291x(91)91061-g

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  5 in total

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4.  A Fos-Jun element in the first intron of an alpha 2u-globulin gene.

Authors:  P van Dijck; K Schoonjans; P Sassone-Corsi; J Auwerx; G Verhoeven
Journal:  Mol Cell Biochem       Date:  1993-08-25       Impact factor: 3.396

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  5 in total

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