Literature DB >> 17146961

A new stilbene glucoside from the roots of Polygonum multiflorum Thunb.

Ming-Lu Xu1, Ming Shan Zheng, Yeon-Kyong Lee, Dong-Cheol Moon, Chong-Soon Lee, Mi-Hee Woo, Byeong-Seon Jeong, Eung Seok Lee, Yurngdong Jahng, Hyeun-Wook Chang, Seung-Ho Lee, Jong-Keun Son.   

Abstract

One new stilbene glucoside (6), along with five known compounds (1-5), were isolated from the roots of Polygonum multiflorum Thumb., and their chemical structures established based on physicochemical and spectroscopic data. Of the compounds, compound 3 showed DNA topoisomerase I and II inhibitory activities.

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Year:  2006        PMID: 17146961     DOI: 10.1007/bf02969276

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN: 0253-6269            Impact factor:   4.946


  8 in total

1.  2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines.

Authors:  Jennifer C Brennan; Michael S Denison; Dirk M Holstege; Prokopios Magiatis; Jerry L Dallas; Elisa G Gutierrez; Anatoly A Soshilov; James R Millam
Journal:  BMC Complement Altern Med       Date:  2013-06-14       Impact factor: 3.659

2.  Antimicrobial activities of the methanol extract, fractions and compounds from Ficus polita Vahl. (Moraceae).

Authors:  Victor Kuete; Justin Kamga; Louis P Sandjo; Bathelemy Ngameni; Herve M P Poumale; Pantaleon Ambassa; Bonaventure T Ngadjui
Journal:  BMC Complement Altern Med       Date:  2011-01-26       Impact factor: 3.659

3.  Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.

Authors:  Supriya Baikar; Nutan Malpathak
Journal:  Pharmacogn Rev       Date:  2010-01

4.  Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum.

Authors:  Qi Wang; Yadan Wang; Yong Li; Binyu Wen; Zhong Dai; Shuangcheng Ma; Yujie Zhang
Journal:  Sci Rep       Date:  2017-12-20       Impact factor: 4.379

5.  In Vitro and In Vivo Anti-Osteoarthritis Effects of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-Glucoside from Polygonum Multiflorum.

Authors:  Po-Wei Tsai; Yi-Hui Lee; Lih-Geeng Chen; Chia-Jung Lee; Ching-Chiung Wang
Journal:  Molecules       Date:  2018-03-03       Impact factor: 4.411

6.  Rapid Determination of Major Compounds in the Ethanol Extract of Geopropolis from Malaysian Stingless Bees, Heterotrigona itama, by UHPLC-Q-TOF/MS and NMR.

Authors:  Lingling Zhao; Mengjiao Yu; Minghui Sun; Xiaofeng Xue; Tongtong Wang; Wei Cao; Liping Sun
Journal:  Molecules       Date:  2017-11-10       Impact factor: 4.411

Review 7.  Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: a review.

Authors:  Longfei Lin; Boran Ni; Hongmei Lin; Miao Zhang; Xuechun Li; Xingbin Yin; Changhai Qu; Jian Ni
Journal:  J Ethnopharmacol       Date:  2014-11-18       Impact factor: 4.360

8.  Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-O-β-d-Glucoside on Gentamicin-Induced Apoptosis in Mouse Cochlear UB/OC-2 Cells.

Authors:  Yu-Hsuan Wen; Jia-Ni Lin; Rong-Shuan Wu; Szu-Hui Yu; Chuan-Jen Hsu; Guo-Fang Tseng; Hung-Pin Wu
Journal:  Molecules       Date:  2020-07-06       Impact factor: 4.411

  8 in total

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