Literature DB >> 17145607

Relationship between autoimmune phenomena and disease stage and therapy in B-cell chronic lymphocytic leukemia.

Wilma Barcellini1, Silvana Capalbo, Rosa Maria Agostinelli, Francesca Romana Mauro, Achille Ambrosetti, Rossella Calori, Agostino Cortelezzi, Luca Laurenti, Enrico Maria Pogliani, Paola Pedotti, Vincenzo Liso, Gabriella Girelli, Franco Mandelli, Alberto Zanella.   

Abstract

The aim of this multicenter GIMEMA study was to correlate autoimmune complications (AIC) in B-cell chronic lymphocytic leukemia (B-CLL) with stage and therapy. Autoimmune hemolytic anemia (129/194 cases) and autoimmune thrombocytopenia (35/194 cases) were typically present in advanced and multi-treated disease. Age over the median, stage C and first and second line therapy were identified as independent risk factors by multivariate analysis. In contrast, non-hematologic AIC (30/194 cases) and the presence of serological markers of autoimmunity were mostly observed in early B-CLL, suggesting different pathogenic mechanisms underlying hematologic and non-hematologic autoimmune phenomena in B-CLL.

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Year:  2006        PMID： 17145607

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  18 in total

1.  Autoimmune hemolytic anemia in patients with chronic lymphocytic leukemia is associated with IgVH status.

Authors:  Carlo Visco; Elisabetta Novella; Eleonora Peotta; Rossella Paolini; Ilaria Giaretta; Francesco Rodeghiero
Journal:  Haematologica       Date:  2010-04-21       Impact factor: 9.941

Review 2.  The ITP syndrome: pathogenic and clinical diversity.

Authors:  Douglas B Cines; James B Bussel; Howard A Liebman; Eline T Luning Prak
Journal:  Blood       Date:  2009-04-24       Impact factor: 22.113

3.  Autoimmune cytopenias in patients with chronic lymphocytic leukaemia treated with ibrutinib in routine clinical practice at an academic medical centre.

Authors:  Paul J Hampel; Melissa C Larson; Brian Kabat; Timothy G Call; Wei Ding; Saad S Kenderian; Deborah Bowen; Justin Boysen; Susan M Schwager; Jose F Leis; Asher A Chanan-Khan; Eli Muchtar; Curtis A Hanson; Susan L Slager; Neil E Kay; Kari G Chaffee; Tait D Shanafelt; Sameer A Parikh
Journal:  Br J Haematol       Date:  2018-08-16       Impact factor: 6.998

Review 4.  Autoimmune complications in chronic lymphocytic leukaemia (CLL).

Authors:  Clive S Zent; Neil E Kay
Journal:  Best Pract Res Clin Haematol       Date:  2010-03       Impact factor: 3.020

5.  Clinical relevance of silent red blood cell autoantibodies.

Authors:  Francesca R Mauro; Fabio Trastulli; Cristiano Alessandri; Guido Valesini; Gianluca Giovannetti; Costantino Riemma; Marika Porrazzo; Sara Pepe; Gioia Colafigli; Maria D Caputo; Maria S De Propris; Anna R Guarini; Gabriella Girelli; Serelina Coluzzi; Robin Foà
Journal:  Haematologica       Date:  2017-09-21       Impact factor: 9.941

6.  Clinical and serological autoimmune complications in chronic lymphocytic leukemia.

Authors:  Cengiz Demir; Ömer Ekinci
Journal:  Wien Klin Wochenschr       Date:  2017-05-05       Impact factor: 1.704

7.  First reported association of chronic lymphocytic leukaemia and interstitial granulomatous dermatitis.

Authors:  Irbaz Bin Riaz; Muhammad Umar Kamal; Robert J Segal; Faiz Anwer
Journal:  BMJ Case Rep       Date:  2016-05-18

8.  Rapid clearance of rituximab may contribute to the continued high incidence of autoimmune hematologic complications of chemoimmunotherapy for chronic lymphocytic leukemia.

Authors:  Clifton C Mo; Ndegwa Njuguna; Paul V Beum; Margaret A Lindorfer; Berengere Vire; Elinor Lee; Gerald Marti; Wyndham H Wilson; Ronald P Taylor; Adrian Wiestner
Journal:  Haematologica       Date:  2013-05-28       Impact factor: 9.941

Review 9.  Murine models of chronic lymphocytic leukaemia: role of microRNA-16 in the New Zealand Black mouse model.

Authors:  Brian J Scaglione; Erica Salerno; Murugabaskar Balan; Frederick Coffman; Pablo Landgraf; Fatima Abbasi; Sergei Kotenko; Gerald E Marti; Elizabeth S Raveche
Journal:  Br J Haematol       Date:  2007-10-17       Impact factor: 6.998

10.  Autoimmune pancreatitis and concurrent small lymphocytic lymphoma: not just a coincidence?

Authors:  Tad Kim; Stephen R Grobmyer; Lisa R Dixon; Robert W Allan; Steven N Hochwald
Journal:  J Gastrointest Surg       Date:  2008-05-28       Impact factor: 3.452
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