Literature DB >> 17144171

Racial and ethnic categories in biomedical research: there is no baby in the bathwater.

Mildred K Cho1.   

Abstract

The use of racial categories in biomedicine has had a long history in the United States. However, social hierarchy and discrimination, justified by purported scientific differences, has also plagued the history of racial categories. Because "race" has some correlation with biological and genetic characteristics, there has been a call not to "throw the baby out with the bathwater" by eliminating race as a research or clinical category. I argue that race is too undefined and fluid to be useful as a proxy for biology or genetics.

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Year:  2006        PMID: 17144171      PMCID: PMC2271137          DOI: 10.1111/j.1748-720x.2006.00061.x

Source DB:  PubMed          Journal:  J Law Med Ethics        ISSN: 1073-1105            Impact factor:   1.718


  17 in total

1.  Population genetic structure of variable drug response.

Authors:  J F Wilson; M E Weale; A C Smith; F Gratrix; B Fletcher; M G Thomas; N Bradman; D B Goldstein
Journal:  Nat Genet       Date:  2001-11       Impact factor: 38.330

2.  "Race": confusion about zoological and social taxonomies, and their places in science.

Authors:  S O Keita; A J Boyce
Journal:  Am J Hum Biol       Date:  2001 Sep-Oct       Impact factor: 1.937

3.  Inferring ethnic origin by means of an STR profile.

Authors:  A L Lowe; A Urquhart; L A Foreman; I W Evett
Journal:  Forensic Sci Int       Date:  2001-06-01       Impact factor: 2.395

4.  The meanings of "race" in the new genomics: implications for health disparities research.

Authors:  S S Lee; J Mountain; B A Koenig
Journal:  Yale J Health Policy Law Ethics       Date:  2001

5.  Genetics. Toward a new vocabulary of human genetic variation.

Authors:  Pamela Sankar; Mildred K Cho
Journal:  Science       Date:  2002-11-15       Impact factor: 47.728

Review 6.  Racial and ethnic differences in response to medicines: towards individualized pharmaceutical treatment.

Authors:  Valentine J Burroughs; Randall W Maxey; Richard A Levy
Journal:  J Natl Med Assoc       Date:  2002-10       Impact factor: 1.798

7.  Genetic structure of human populations.

Authors:  Noah A Rosenberg; Jonathan K Pritchard; James L Weber; Howard M Cann; Kenneth K Kidd; Lev A Zhivotovsky; Marcus W Feldman
Journal:  Science       Date:  2002-12-20       Impact factor: 47.728

8.  Conceptualizing human variation.

Authors:  S O Y Keita; R A Kittles; C D M Royal; G E Bonney; P Furbert-Harris; G M Dunston; C N Rotimi
Journal:  Nat Genet       Date:  2004-11       Impact factor: 38.330

Review 9.  Prospects and limits of pharmacogenetics: the thiopurine methyl transferase (TPMT) experience.

Authors:  Jan van Aken; Mechtild Schmedders; Günter Feuerstein; Regine Kollek
Journal:  Am J Pharmacogenomics       Date:  2003

10.  Categorization of humans in biomedical research: genes, race and disease.

Authors:  Neil Risch; Esteban Burchard; Elad Ziv; Hua Tang
Journal:  Genome Biol       Date:  2002-07-01       Impact factor: 13.583

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  10 in total

1.  The ambiguous meanings of the racial/ethnic categories routinely used in human genetics research.

Authors:  Linda M Hunt; Mary S Megyesi
Journal:  Soc Sci Med       Date:  2007-10-23       Impact factor: 4.634

2.  Discussing race-related limitations of genomic testing for colon cancer risk: implications for education and counseling.

Authors:  Morgan N Butrick; Lauren Vanhusen; Kara-Grace Leventhal; Gillian W Hooker; Rachel Nusbaum; Beth N Peshkin; Yasmin Salehizadeh; Jessica Pavlick; Marc D Schwartz; Kristi D Graves
Journal:  Soc Sci Med       Date:  2014-05-15       Impact factor: 4.634

3.  Human difference in the genomic era: Facilitating a socially responsible dialogue.

Authors:  Sarah Knerr; Edward Ramos; Juleigh Nowinski; Keianna Dixon; Vence L Bonham
Journal:  BMC Med Genomics       Date:  2010-05-26       Impact factor: 3.063

4.  Community-based dialogue: engaging communities of color in the United states' genetics policy conversation.

Authors:  Vence L Bonham; Toby Citrin; Stephen M Modell; Tené Hamilton Franklin; Esther W B Bleicher; Leonard M Fleck
Journal:  J Health Polit Policy Law       Date:  2009-06       Impact factor: 2.265

5.  Inclusion of women, minorities, and children in clinical trials: opinions of research ethics board administrators.

Authors:  Holly A Taylor
Journal:  J Empir Res Hum Res Ethics       Date:  2009-06       Impact factor: 1.742

6.  Implementation of NIH inclusion guidelines: survey of NIH study section members.

Authors:  Holly A Taylor
Journal:  Clin Trials       Date:  2008       Impact factor: 2.486

7.  Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records.

Authors:  Logan Dumitrescu; Marylyn D Ritchie; Kristin Brown-Gentry; Jill M Pulley; Melissa Basford; Joshua C Denny; Jorge R Oksenberg; Dan M Roden; Jonathan L Haines; Dana C Crawford
Journal:  Genet Med       Date:  2010-10       Impact factor: 8.822

8.  Two Threats to Precision Medicine Equity.

Authors:  Dayna Bowen Matthew
Journal:  Ethn Dis       Date:  2019-12-12       Impact factor: 2.006

Review 9.  Blood politics, ethnic identity, and racial misclassification among American Indians and Alaska Natives.

Authors:  Emily A Haozous; Carolyn J Strickland; Janelle F Palacios; Teshia G Arambula Solomon
Journal:  J Environ Public Health       Date:  2014-02-10

Review 10.  Racial/ethnic representation in lifestyle weight loss intervention studies in the United States: A systematic review.

Authors:  Christina F Haughton; Valerie J Silfee; Monica L Wang; Andrea C Lopez-Cepero; David P Estabrook; Christine Frisard; Milagros C Rosal; Sherry L Pagoto; Stephenie C Lemon
Journal:  Prev Med Rep       Date:  2018-02-02
  10 in total

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