Literature DB >> 17142876

Is the search for alternative sources of human pluripotent stem cells a mistake?

Mary Devereaux1.   

Abstract

One response to the controversy in the United States over the moral status of the early embryo has been the proposal that scientists search for alternative sources of pluripotent stem cells. Is this a good idea? The present article argues that it is not. Following a brief look at the ethical standing of the four proposals assessed by the President's Council on Bioethics in 2005, the author addresses the fundamental question of the wisdom of pursuing alternatives to current methods of stem cell derivation. The author concludes that, given the poor prospects for finding alternatives that are both scientifically and ethically sound, and the costs of diverting energy and resources from established embryonic methods, further investment in the search for alternative methods is unwise.

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Year:  2005        PMID: 17142876     DOI: 10.1385/SCR:1:4:331

Source DB:  PubMed          Journal:  Stem Cell Rev        ISSN: 1550-8943            Impact factor:   5.739


  4 in total

1.  Stem cell test tried on mice saves embryo; technique could shift debate on humans.

Authors:  Nicholas Wade
Journal:  N Y Times Web       Date:  2005-10-17

Review 2.  Ethical issues in using and not using embryonic stem cells.

Authors:  Frances M Kamm
Journal:  Stem Cell Rev       Date:  2005-12       Impact factor: 5.739

3.  Rescuing human embryonic stem cell research: the Blastocyst Transfer Method.

Authors:  S Matthew Liao
Journal:  Am J Bioeth       Date:  2005 Nov-Dec       Impact factor: 11.229

4.  Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts.

Authors:  Alexander Meissner; Rudolf Jaenisch
Journal:  Nature       Date:  2005-10-16       Impact factor: 49.962

  4 in total

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