| Literature DB >> 17141623 |
Abstract
The link between inflammation and diabetes is well established, but the nature of the link is unresolved. Obesity, inflammation, and insulin resistance are major characteristics of diabetes. A study by Flier and colleagues () identifies Toll-like receptor 4 signaling activated by fatty acids as part of that link. This receptor mediates inflammatory events and insulin resistance in peripheral organs.Entities:
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Year: 2006 PMID： 17141623 DOI： 10.1016/j.cmet.2006.11.008
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287