Literature DB >> 17139109

A new citryl glycoside from Gastrodia elata and its inhibitory activity on GABA transaminase.

Jung-Hyun Choi1, Dong-Ung Lee.   

Abstract

A new citryl glycoside, trimethylcitryl-beta-D-galactopyranoside (1) along with a known phenolic compound, gastrodigenin (2) have been isolated from the active fraction of the rhizomes of Gastrodia elata (Orchidaceae). Their structures were elucidated on the basis of spectroscopic data and chemical reaction. 1 inhibited GABA transaminase activity by 56.8% at the final concentration of 10 microg/ml.

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Year:  2006        PMID： 17139109     DOI： 10.1248/cpb.54.1720

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  5 in total

1.  Protective effects of gastrodia elata on aluminium-chloride-induced learning impairments and alterations of amino acid neurotransmitter release in adult rats.

Authors:  He Shuchang; Niu Qiao; Niu Piye; He Mingwei; Sun Xiaoshu; Shao Feng; Wang Sheng; Mark Opler
Journal:  Restor Neurol Neurosci       Date:  2008       Impact factor: 2.406

Review 2.  Gastrodiae Rhizoma (tiān má): a review of biological activity and antidepressant mechanisms.

Authors:  Pei-Ju Chen; Lee-Yan Sheen
Journal:  J Tradit Complement Med       Date:  2011-10

3.  Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells.

Authors:  Victor Kuete; Louis P Sandjo; Armelle T Mbaveng; Jackson A Seukep; Bonaventure T Ngadjui; Thomas Efferth
Journal:  BMC Complement Altern Med       Date:  2015-09-04       Impact factor: 3.659

4.  Simultaneous Qualitative Assessment and Quantitative Analysis of Metabolites (Phenolics, Nucleosides and Amino Acids) from the Roots of Fresh Gastrodia elata Using UPLC-ESI-Triple Quadrupole Ion MS and ESI- Linear Ion Trap High-Resolution MS.

Authors:  Sha Chen; Jun Qiu Liu; Hui Xiao; Jun Zhang; An Liu
Journal:  PLoS One       Date:  2016-03-08       Impact factor: 3.240

Review 5.  Neuropharmacological Potential of Gastrodia elata Blume and Its Components.

Authors:  Jung-Hee Jang; Yeonghoon Son; Seong Soo Kang; Chun-Sik Bae; Jong-Choon Kim; Sung-Ho Kim; Taekyun Shin; Changjong Moon
Journal:  Evid Based Complement Alternat Med       Date:  2015-10-12       Impact factor: 2.629
  5 in total

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