Literature DB >> 17137549

Clinical inquiries: What blood tests help diagnose celiac disease?

Bonzo K Reddick1, Karen Crowell, Belinda Fu.   

Abstract

Histological confirmation of infiltrative lesions via small bowel biopsy is the gold standard for diagnosing celiac disease. Four serum antibody assays may serve as a first-step diagnostic tool to identify biopsy candidates: immunoglobulin A tissue transglutaminase (IgA tTG), IgA endomysial antibody (IgA EMA), IgA antigliadin antibody (IgA AGA), and IgG antigliadin antibody (IgG AGA). IgA tTG and IgA EMA offer the best diagnostic accuracy. Patients with selective IgA deficiency may have falsely negative IgA assays (strength of recommendation [SOR]: B, based on a systematic review, multiple small cross-sectional studies, and expert opinion).

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Year:  2006        PMID: 17137549

Source DB:  PubMed          Journal:  J Fam Pract        ISSN: 0094-3509            Impact factor:   0.493


  6 in total

Review 1.  A biological substrate for somatoform disorders: importance of pathophysiology.

Authors:  Joel E Dimsdale; Robert Dantzer
Journal:  Psychosom Med       Date:  2007-12       Impact factor: 4.312

2.  A muslim family with several members with celiac disease and other autoimmune disorders.

Authors:  Yulia Treister-Goltzman; Roni Peleg
Journal:  J Immigr Minor Health       Date:  2015-04

3.  Feasibility of a finger prick-based self-testing kit in first- and second-degree relatives of children with coeliac disease.

Authors:  Judith Pichler; Matthias Zilbauer; Franco Torrente; Robert Heuschkel; Alan Phillips; Camilla Salvestrini
Journal:  World J Gastroenterol       Date:  2011-04-14       Impact factor: 5.742

4.  Does celiac disease trigger autoimmune thyroiditis?

Authors:  Leonidas H Duntas
Journal:  Nat Rev Endocrinol       Date:  2009-04       Impact factor: 43.330

5.  Diagnosing celiac disease in patients with a history of lymphoma: factors that matter.

Authors:  Karel Balihar; Jana Kozeluhova; Vaclav Hejda; Michal Krcma; Daniel Lysak; Jitka Gorcikova; Ondrej Hes; Martin Matejovic
Journal:  Wien Klin Wochenschr       Date:  2013-10-23       Impact factor: 1.704

6.  Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset.

Authors:  Victoria K Baxter; Gillian C Shaw; Nathaniel P Sotuyo; Cathy S Carlson; Erik J Olson; M Christine Zink; Joseph L Mankowski; Robert J Adams; Eric K Hutchinson; Kelly A Metcalf Pate
Journal:  PLoS One       Date:  2013-12-06       Impact factor: 3.240

  6 in total

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