| Literature DB >> 17136891 |
Hideaki Ui1, Kazuro Shiomi, Hideaki Suzuki, Hiroko Hatano, Hiromi Morimoto, Yuichi Yamaguchi, Rokuro Masuma, Kimitoshi Sakamoto, Kiyoshi Kita, Hideto Miyoshi, Hiroshi Tomoda, Haruo Tanaka, Satoshi Omura.
Abstract
A new NADH-fumarate reductase inhibitor, paecilaminol, was isolated from the cultured broth of a fungus Paecilomyces sp. FKI-0550. It is an amino alcohol compound, the structure being established as 2-amino-14,16-dimethyl-3-octadecanol. Paecilaminol exhibited an IC50 value of 5.1 microM against Ascaris suum NADH-fumarate reductase.Entities:
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Year: 2006 PMID： 17136891 DOI： 10.1038/ja.2006.79
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649