Literature DB >> 17136129

Shiga toxin 'goes retro' in human primary kidney cells.

J C Paton1, A W Paton.   

Abstract

The pathway and the efficiency of intracellular trafficking of Shiga toxin differ between cell types, and this impacts on susceptibility to cytotoxicity. Warnier et al. demonstrate that in cell types targeted during human disease, Shiga toxin undergoes retrograde transport via the trans-Golgi network to the endoplasmic reticulum, albeit less efficiently than in HeLa cells.

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Year:  2006        PMID： 17136129     DOI： 10.1038/sj.ki.5001954

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  6 in total

Review 1.  Facing glycosphingolipid-Shiga toxin interaction: dire straits for endothelial cells of the human vasculature.

Authors:  Andreas Bauwens; Josefine Betz; Iris Meisen; Björn Kemper; Helge Karch; Johannes Müthing
Journal:  Cell Mol Life Sci       Date:  2012-07-06       Impact factor: 9.261

2.  Evaluation of Fab and F(ab')2 fragments and isotype variants of a recombinant human monoclonal antibody against Shiga toxin 2.

Authors:  Donna E Akiyoshi; Abhineet S Sheoran; Curtis M Rich; L Richard; Susan Chapman-Bonofiglio; Saul Tzipori
Journal:  Infect Immun       Date:  2010-01-19       Impact factor: 3.441

3.  Protection of mice against Shiga toxin 2 (Stx2)-associated damage by maternal immunization with a Brucella lumazine synthase-Stx2 B subunit chimera.

Authors:  María Pilar Mejias; Gabriel Cabrera; Romina Jimena Fernández-Brando; Ariela Baschkier; Giselle Ghersi; Maria Jimena Abrey-Recalde; Elizabeth Miliwebsky; Roberto Meiss; Fernando Goldbaum; Vanesa Zylberman; Marta Rivas; Marina Sandra Palermo
Journal:  Infect Immun       Date:  2014-01-13       Impact factor: 3.441

4.  Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS.

Authors:  Morena S Havira; Atri Ta; Puja Kumari; Chengliang Wang; Ashley J Russo; Jianbin Ruan; Vijay A Rathinam; Sivapriya Kailasan Vanaja
Journal:  Sci Immunol       Date:  2020-11-27

5.  A therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunit.

Authors:  Michael Taylor; Tuhina Banerjee; Fernando Navarro-Garcia; Jazmin Huerta; Shane Massey; Mansfield Burlingame; Abhay H Pande; Suren A Tatulian; Ken Teter
Journal:  PLoS One       Date:  2011-04-19       Impact factor: 3.240

6.  Crosstalk between Human Microvascular Endothelial Cells and Tubular Epithelial Cells Modulates Pro-Inflammatory Responses Induced by Shiga Toxin Type 2 and Subtilase Cytotoxin.

Authors:  Romina S Álvarez; Carolina Jancic; Nicolás Garimano; Flavia Sacerdoti; Adrienne W Paton; James C Paton; Cristina Ibarra; María M Amaral
Journal:  Toxins (Basel)       Date:  2019-11-07       Impact factor: 4.546
  6 in total

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