| Literature DB >> 17134881 |
Carolina Serena1, Marçal Mariné, Rita Marimon, Francisco Javier Pastor, Josep Guarro.
Abstract
Blastoschizomyces capitatus is an emerging pathogenic fungus that can cause deep invasive diseases in neutropenic patients. We developed a model of disseminated blastoschizomycosis in immunosuppressed mice to evaluate the effectiveness of amphotericin B, flucytosine, fluconazole and voriconazole. High-dose fluconazole was the most effective drug at prolonging the survival of mice and at reducing fungal burden in the kidneys, spleen and liver.Entities:
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Year: 2006 PMID： 17134881 DOI： 10.1016/j.ijantimicag.2006.08.025
Source DB: PubMed Journal: Int J Antimicrob Agents ISSN： 0924-8579 Impact factor: 5.283