Literature DB >> 17132852

International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor.

David D Moore1, Shigeaki Kato, Wen Xie, David J Mangelsdorf, Daniel R Schmidt, Rui Xiao, Steven A Kliewer.   

Abstract

The nuclear receptors of the NR1H and NR1I subgroups include the constitutive androstane receptor, pregnane X receptor, farnesoid X receptors, liver X receptors, and vitamin D receptor. The newly emerging functions of these related receptors are under the control of metabolic pathways, including metabolism of xenobiotics, bile acids, cholesterol, and calcium. This review summarizes results of structural, pharmacologic, and genetic studies of these receptors.

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Year:  2006        PMID： 17132852     DOI： 10.1124/pr.58.4.6

Source DB:  PubMed          Journal:  Pharmacol Rev        ISSN： 0031-6997            Impact factor:   25.468


  56 in total

1.  The role of nuclear receptors in the kidney in obesity and metabolic syndrome.

Authors:  Claudia Tovar-Palacio; Nimbe Torres; Andrea Diaz-Villaseñor; Armando R Tovar
Journal:  Genes Nutr       Date:  2012-04-25       Impact factor: 5.523

Review 2.  Liver x receptors in atherosclerosis and inflammation.

Authors:  Seung-Soon Im; Timothy F Osborne
Journal:  Circ Res       Date:  2011-04-15       Impact factor: 17.367

Review 3.  The nuclear hormone receptor family round the clock.

Authors:  Michèle Teboul; Fabienne Guillaumond; Aline Gréchez-Cassiau; Franck Delaunay
Journal:  Mol Endocrinol       Date:  2008-07-24

Review 4.  The orphan nuclear receptors at their 25-year reunion.

Authors:  Shannon E Mullican; Joanna R Dispirito; Mitchell A Lazar
Journal:  J Mol Endocrinol       Date:  2013-11-26       Impact factor: 5.098

Review 5.  Allosteric pathways in nuclear receptors - Potential targets for drug design.

Authors:  Elias J Fernandez
Journal:  Pharmacol Ther       Date:  2017-10-31       Impact factor: 12.310

Review 6.  Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.

Authors:  Andrzej T Slominski; Anna A Brożyna; Michal A Zmijewski; Wojciech Jóźwicki; Anton M Jetten; Rebecca S Mason; Robert C Tuckey; Craig A Elmets
Journal:  Lab Invest       Date:  2017-02-20       Impact factor: 5.662

7.  Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain.

Authors:  Natalia Varlakhanova; Chelsea Snyder; Soumia Jose; Johnnie B Hahm; Martin L Privalsky
Journal:  Mol Cell Biol       Date:  2010-01-11       Impact factor: 4.272

8.  Impact of the haplotypes of the human pregnane X receptor gene on the basal and St John's wort-induced activity of cytochrome P450 3A4 enzyme.

Authors:  Xue-Ding Wang; Jia-Li Li; Qi-Biao Su; Su Guan; Jie Chen; Jun Du; Yu-Wen He; Jun Zeng; Jin-Xin Zhang; Xiao Chen; Min Huang; Shu-Feng Zhou
Journal:  Br J Clin Pharmacol       Date:  2008-12-01       Impact factor: 4.335

Review 9.  Bile acid transporters in health and disease.

Authors:  A Kosters; S J Karpen
Journal:  Xenobiotica       Date:  2008-07       Impact factor: 1.908

Review 10.  Targeting truncated RXRα for cancer therapy.

Authors:  Xiaokun Zhang; Hu Zhou; Ying Su
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2015-10-21       Impact factor: 3.848
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