| Literature DB >> 17132850 |
Pierre Germain1, Pierre Chambon, Gregor Eichele, Ronald M Evans, Mitchell A Lazar, Mark Leid, Angel R De Lera, Reuben Lotan, David J Mangelsdorf, Hinrich Gronemeyer.
Abstract
Retinoid is a term for compounds that bind to and activate retinoic acid receptors (RARalpha, RARbeta, and RARgamma), members of the nuclear hormone receptor superfamily. The most important endogenous retinoid is all-trans-retinoic acid. Retinoids regulate a wide variety of essential biological processes, such as vertebrate embryonic morphogenesis and organogenesis, cell growth arrest, differentiation and apoptosis, and homeostasis, as well as their disorders. This review summarizes the considerable amount of knowledge generated on these receptors.Entities:
Mesh:
Substances:
Year: 2006 PMID: 17132850 DOI: 10.1124/pr.58.4.4
Source DB: PubMed Journal: Pharmacol Rev ISSN: 0031-6997 Impact factor: 25.468