Literature DB >> 1713183

Localisation of hyaluronan in the human intestinal wall.

B Gerdin1, R Hällgren.   

Abstract

By using biotin labelled proteoglycan core protein and an avidin enzyme system, hyaluronan (hyaluronic acid) was visualised in specimens of human jejunum. Intense staining for hyaluronan was seen in the loose connective tissue of the villi and of lamina propria while the epithelial layer was unstained. The muscularis mucosae showed only faint staining. The accumulation of hyaluronan in the subepithelial layer of the jejunal mucosa indicates that the previously reported high jejunal secretion of hyaluronan is due to passive diffusion from the subepithelial interstitium. The physicochemical characteristics conferred by hyaluronan may be important for the villi function.

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Year:  1991        PMID： 1713183      PMCID： PMC1378991          DOI： 10.1136/gut.32.7.760

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  12 in total

1.  Hyaluronic acid and type III procollagen peptide in jejunal perfusion fluid as markers of connective tissue turnover.

Authors:  J F Colombel; R Hällgren; A Engström-Laurent; J C Rambaud
Journal:  Gastroenterology       Date:  1989-01       Impact factor: 22.682

2.  Accumulation of hyaluronic acid in the alveolar interstitial tissue in bleomycin-induced alveolitis.

Authors:  O Nettelbladt; J Bergh; M Schenholm; A Tengblad; R Hällgren
Journal:  Am Rev Respir Dis       Date:  1989-03

3.  Collagen synthesis by human intestinal smooth muscle cells in culture.

Authors:  M F Graham; D E Drucker; R F Diegelmann; C O Elson
Journal:  Gastroenterology       Date:  1987-02       Impact factor: 22.682

4.  The hyaluronic acid binding region as a specific probe for the localization of hyaluronic acid in tissue sections. Application to chick embryo and rat brain.

Authors:  J A Ripellino; M M Klinger; R U Margolis; R K Margolis
Journal:  J Histochem Cytochem       Date:  1985-10       Impact factor: 2.479

5.  Signs of increased leakage over the jejunal mucosa during gliadin challenge of patients with coeliac disease.

Authors:  B Lavö; L Knutson; L Lööf; B Odlind; R Hällgren
Journal:  Gut       Date:  1990-02       Impact factor: 23.059

6.  Affinity chromatography on immobilized hyaluronate and its application to the isolation of hyaluronate binding properties from cartilage.

Authors:  A Tengblad
Journal:  Biochim Biophys Acta       Date:  1979-06-19

7.  Effect of increased hydrostatic pressure on lymphatic elimination of hyaluronan from sheep lung.

Authors:  L Lebel; L Smith; B Risberg; B Gerdin; T C Laurent
Journal:  J Appl Physiol (1985)       Date:  1988-04

8.  Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycan as a specific probe.

Authors:  R Tammi; J A Ripellino; R U Margolis; M Tammi
Journal:  J Invest Dermatol       Date:  1988-03       Impact factor: 8.551

9.  Concentration and relative molecular mass of hyaluronate in lymph and blood.

Authors:  A Tengblad; U B Laurent; K Lilja; R N Cahill; A Engström-Laurent; J R Fraser; H E Hansson; T C Laurent
Journal:  Biochem J       Date:  1986-06-01       Impact factor: 3.857

10.  Hyaluronic acid accumulation and redistribution in rejecting rat kidney graft. Relationship to the transplantation edema.

Authors:  R Hällgren; B Gerdin; G Tufveson
Journal:  J Exp Med       Date:  1990-06-01       Impact factor: 14.307
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  7 in total

1.  Hyaluronidase 2 (HYAL2) is expressed in endothelial cells, as well as some specialized epithelial cells, and is required for normal hyaluronan catabolism.

Authors:  Biswajit Chowdhury; Richard Hemming; Sana Faiyaz; Barbara Triggs-Raine
Journal:  Histochem Cell Biol       Date:  2015-10-29       Impact factor: 4.304

Review 2.  Extracellular matrix components in intestinal development.

Authors:  P Simon-Assmann; M Kedinger; A De Arcangelis; V Rousseau; P Simo
Journal:  Experientia       Date:  1995-09-29

3.  Hyaluronidase inhibits reactive adipogenesis and inflammation of colon and skin.

Authors:  Tatsuya Dokoshi; Ling-Juan Zhang; Teruaki Nakatsuji; Christopher A Adase; James A Sanford; Rudolph D Paladini; Hiroki Tanaka; Mikihiro Fujiya; Richard L Gallo
Journal:  JCI Insight       Date:  2018-11-02

Review 4.  The role of hyaluronan in innate defense responses of the intestine.

Authors:  Carol A de la Motte; Sean P Kessler
Journal:  Int J Cell Biol       Date:  2015-03-30

5.  The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.

Authors:  M Mehić; V K de Sa; S Hebestreit; C-H Heldin; P Heldin
Journal:  Oncogenesis       Date:  2017-06-12       Impact factor: 7.485

6.  Combined Treatment with Hyaluronic Acid and Mesalamine Protects Rats from Inflammatory Bowel Disease Induced by Intracolonic Administration of Trinitrobenzenesulfonic Acid.

Authors:  Chih-Tung Chiu; Sheng-Nan Kuo; Shao-Wen Hung; Cheng-Yao Yang
Journal:  Molecules       Date:  2017-05-30       Impact factor: 4.411

7.  Modulation of Gut Barrier Functions in Ulcerative Colitis by Hyaluronic Acid System.

Authors:  Niranjan G Kotla; Isma Liza Mohd Isa; Swetha Rasala; Secil Demir; Rajbir Singh; Becca V Baby; Samantha K Swamy; Peter Dockery; Venkatakrishna R Jala; Yury Rochev; Abhay Pandit
Journal:  Adv Sci (Weinh)       Date:  2021-11-10       Impact factor: 16.806
  7 in total

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