[The effect of the time of death on the reactivity of rat caudal artery regulated by Bay-K 8644 (an agonist directly affecting the Ca channel)].

The research was conducted on Bay-K 8644-perfused rat caudal arteries in four different time groups. Investigations using the direct Ca channel agonist demonstrated a time-dependent decrease of arterial reactivity. The authors determined that the contractions of the smooth muscle coat preceded by an increased cytoplasm Ca++ level were significantly prolonged by the activation of direct Ca++ inflow from the extracellular space.