| Literature DB >> 17130898 |
J Judy Chang1, Sharon R Lewin.
Abstract
Hepatitis B virus (HBV) infection is a non-cytopathic hepatotropic virus that can lead to severe liver disease including acute hepatitis, cirrhosis and hepatocellular carcinoma. Successful clearance of the virus as well as the establishment of liver disease is largely driven by a complex interaction between the virus and the host immune response. In this review, the immunological events, including both the innate and adaptive immune response are discussed in the setting of both acute and chronic HBV infection and liver disease.Entities:
Mesh:
Substances:
Year: 2006 PMID: 17130898 DOI: 10.1038/sj.icb.7100009
Source DB: PubMed Journal: Immunol Cell Biol ISSN: 0818-9641 Impact factor: 5.126