Literature DB >> 17130422

Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging.

H V Danesh-Meyer1, H Birch, J Y-F Ku, S Carroll, G Gamble.   

Abstract

In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.

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Year:  2006        PMID: 17130422     DOI: 10.1212/01.wnl.0000244490.07925.8b

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  53 in total

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9.  Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic mice.

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