Literature DB >> 17129824

Optical biosensors: where next and how soon?

Matthew A Cooper1.   

Abstract

From a direct comparison of the technical benefits of labelled reporter assays with the benefits of label-free assays, label-free appears to have significant advantages. Faster assay development times; accurate, high information content data; and less interference from labels. However, optical label-free platforms have not yet made a major impact in the drug discovery technology markets; are often viewed as having poor throughput, limited application; and are difficult to learn and use effectively.

Mesh:

Year:  2006        PMID: 17129824     DOI: 10.1016/j.drudis.2006.10.003

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  17 in total

Review 1.  Interferometric methods for label-free molecular interaction studies.

Authors:  Amanda Kussrow; Carolyn S Enders; Darryl J Bornhop
Journal:  Anal Chem       Date:  2011-11-07       Impact factor: 6.986

2.  Free-solution interaction assay of carbonic anhydrase to its inhibitors using back-scattering interferometry.

Authors:  Ereny F Morcos; Amanda Kussrow; Carolyn Enders; Darryl Bornhop
Journal:  Electrophoresis       Date:  2010-11       Impact factor: 3.535

3.  Identifying and Validating MYC:Protein Interactors in Pursuit of Novel Anti-MYC Therapies.

Authors:  Diana Resetca; Alannah S MacDonald; Tristan M G Kenney; Yong Wei; Cheryl H Arrowsmith; Brian Raught; Linda Z Penn
Journal:  Methods Mol Biol       Date:  2021

4.  Label-free detection of G protein-SNARE interactions and screening for small molecule modulators.

Authors:  Christopher A Wells; Katherine M Betke; Craig W Lindsley; Heidi E Hamm
Journal:  ACS Chem Neurosci       Date:  2012-01-18       Impact factor: 4.418

5.  New LIC vectors for production of proteins from genes containing rare codons.

Authors:  William H Eschenfeldt; Magdalena Makowska-Grzyska; Lucy Stols; Mark I Donnelly; Robert Jedrzejczak; Andrzej Joachimiak
Journal:  J Struct Funct Genomics       Date:  2013-09-22

6.  Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes.

Authors:  Magdalena Makowska-Grzyska; Youngchang Kim; Ruiying Wu; Rosemarie Wilton; Deviprasad R Gollapalli; Ximi K Wang; Rongguang Zhang; Robert Jedrzejczak; Jamey C Mack; Natalia Maltseva; Rory Mulligan; T Andrew Binkowski; Piotr Gornicki; Misty L Kuhn; Wayne F Anderson; Lizbeth Hedstrom; Andrzej Joachimiak
Journal:  Biochemistry       Date:  2012-07-25       Impact factor: 3.162

7.  The Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognition.

Authors:  Chris P Williams; Nicole Schueller; Colin A Thompson; Marlene van den Berg; Simon D Van Haren; Ralf Erdmann; Charles S Bond; Ben Distel; Wolfgang Schliebs; Matthias Wilmanns; Will A Stanley
Journal:  BMC Biochem       Date:  2011-03-04       Impact factor: 4.059

Review 8.  Total internal reflection fluorescence quantification of receptor pharmacology.

Authors:  Ye Fang
Journal:  Biosensors (Basel)       Date:  2015-04-27

9.  Surface plasmon resonance imaging for real-time, label-free analysis of protein interactions with carbohydrate microarrays.

Authors:  Rositsa Karamanska; Jonathan Clarke; Ola Blixt; James I Macrae; Jiquan Q Zhang; Paul R Crocker; Nicolas Laurent; Adam Wright; Sabine L Flitsch; David A Russell; Robert A Field
Journal:  Glycoconj J       Date:  2007-06-16       Impact factor: 2.916

10.  Cellular cofactors of lentiviral integrase: from target validation to drug discovery.

Authors:  Oliver Taltynov; Belete A Desimmie; Jonas Demeulemeester; Frauke Christ; Zeger Debyser
Journal:  Mol Biol Int       Date:  2012-08-07
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