Literature DB >> 17129773

ER targeting signals: more than meets the eye?

Eileithyia Swanton1, Stephen High.   

Abstract

The signal sequences that target newly synthesized proteins to the endoplasmic reticulum are highly variable; however, the functional significance of this diversity has remained obscure. In this issue, Kang et al. (2006) report that variability in signal sequences allows the cell to selectively regulate the translocation of proteins into the endoplasmic reticulum in a substrate-specific manner.

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Year:  2006        PMID: 17129773     DOI: 10.1016/j.cell.2006.11.018

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  7 in total

1.  How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: lessons from interleukin-15 (IL-15)/IL-15 receptor alpha.

Authors:  Erwin H Duitman; Zane Orinska; Elena Bulanova; Ralf Paus; Silvia Bulfone-Paus
Journal:  Mol Cell Biol       Date:  2008-05-27       Impact factor: 4.272

2.  Structural basis for leucine-rich nuclear export signal recognition by CRM1.

Authors:  Xiuhua Dong; Anindita Biswas; Katherine E Süel; Laurie K Jackson; Rita Martinez; Hongmei Gu; Yuh Min Chook
Journal:  Nature       Date:  2009-04-01       Impact factor: 49.962

Review 3.  Clearing Traffic Jams During Protein Translocation Across Membranes.

Authors:  Lihui Wang; Yihong Ye
Journal:  Front Cell Dev Biol       Date:  2021-01-08

Review 4.  Daylight-PDT: everything under the sun.

Authors:  Dana Beiki; Ian M Eggleston; Charareh Pourzand
Journal:  Biochem Soc Trans       Date:  2022-04-29       Impact factor: 4.919

5.  The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation.

Authors:  Yiguo Zhang; John M Lucocq; Masayuki Yamamoto; John D Hayes
Journal:  Biochem J       Date:  2007-12-01       Impact factor: 3.857

6.  Modular organization and combinatorial energetics of proline-tyrosine nuclear localization signals.

Authors:  Katherine E Süel; Hongmei Gu; Yuh Min Chook
Journal:  PLoS Biol       Date:  2008-06-03       Impact factor: 8.029

7.  SGTA regulates the cytosolic quality control of hydrophobic substrates.

Authors:  Lydia Wunderley; Pawel Leznicki; Aishwarya Payapilly; Stephen High
Journal:  J Cell Sci       Date:  2014-09-01       Impact factor: 5.285

  7 in total

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