Literature DB >> 17127739

Polyclonal plasma cell proliferation with marked hypergammaglobulinemia and multiple autoantibodies.

Lin Li1, Peihong Hsu, Keyur Patel, Yasi Saffari, Ida Ashley, Judith Brody.   

Abstract

A 77-yr-old man presented with marked peripheral blood and bone marrow plasmacytosis, marked hypergammaglobulinemia, and multiple autoantibodies. Serum protein immunofixation and immunophenotyping of bone marrow plasma cells by flow cytometry and immunohistochemistry disclosed polyclonal proliferation of plasma cells at various stages of differentiation. The presence of multiple autoantibodies in the patient's serum suggests that an autoimmune disease underlies the polyclonal proliferation of plasma cells.

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Year:  2006        PMID: 17127739

Source DB:  PubMed          Journal:  Ann Clin Lab Sci        ISSN: 0091-7370            Impact factor:   1.256


  5 in total

Review 1.  Peripheral blood polyclonal plasmacytosis mimicking plasma cell leukemia in patients with angioimmunoblastic T-cell lymphoma: report of 3 cases and review of the literature.

Authors:  Arshad N Ahsanuddin; Russell K Brynes; Shiyong Li
Journal:  Int J Clin Exp Pathol       Date:  2011-04-18

2.  A case of CD10-negative angioimmunoblastic T cell lymphoma with leukemic change and increased plasma cells mimicking plasma cell leukemia: A case report.

Authors:  Yasushi Adachi; Takuya Hino; Masahiko Ohsawa; Kazuhito Ueki; Tomoko Murao; Ming Li; Yunze Cui; Mitsuhiko Okigaki; Mitsuhiro Ito; Susumu Ikehara
Journal:  Oncol Lett       Date:  2015-07-14       Impact factor: 2.967

3.  Disseminated Cryptococcal infection in an immunocompetent host mimicking plasma cell disorder: a case report and literature review.

Authors:  Muhammad Bilal Abid; Sanjay De Mel; Michelle Poon Limei
Journal:  Clin Case Rep       Date:  2015-02-28

4.  Clinical manifestation of angioimmunoblastic T-cell lymphoma with exuberant plasmacytosis.

Authors:  Hisao Nagoshi; Junya Kuroda; Tsutomu Kobayashi; Saori Maegawa; Yoshiaki Chinen; Miki Kiyota; Ryuko Nakayama; Shinsuke Mizutani; Yuji Shimura; Mio Yamamoto-Sugitani; Yosuke Matsumoto; Shigeo Horiike; Masafumi Taniwaki
Journal:  Int J Hematol       Date:  2013-08-15       Impact factor: 2.319

5.  Klebsiella pneumoniae associated extreme plasmacytosis.

Authors:  Yeonsook Moon; Woo Ri Jang; Hyeon Gyu Yi; In Seo Park; Chung Hyun Nahm; Jong Weon Choi; Jin Ju Kim; Seung Baik Han
Journal:  Infect Chemother       Date:  2013-12-27
  5 in total

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