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Literature DB >> 17127678

GOlorize: a Cytoscape plug-in for network visualization with Gene Ontology-based layout and coloring.

Olivier Garcia¹, Cosmin Saveanu, Melissa Cline, Micheline Fromont-Racine, Alain Jacquier, Benno Schwikowski, Tero Aittokallio.

Abstract

UNLABELLED: We have implemented a graph layout algorithm that exposes Gene Ontology (GO) class structure on the network nodes. It can be used in conjunction with BiNGO plug-in to Cytoscape, which finds the GO categories over-represented in a given network. Our plug-in, named GOlorize, first highlights the class members with category-specific color-coding and then constructs an enhanced visualization of the network using a class-directed layout algorithm. AVAILABILITY: http://www.cytoscape.org/plugins2.php. SUPPLEMENTARY INFORMATION: Installation instructions and tutorial at http://www.cytoscape.org/plugins/GOlorize/GOlorizeUserGuide.pdf.

Mesh：

Substances：
Proteome

Year: 2006 PMID： 17127678 DOI： 10.1093/bioinformatics/btl605

Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937

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Cited

43 in total

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Review 3. Network integration and graph analysis in mammalian molecular systems biology.

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7. Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.

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