| Literature DB >> 17127517 |
Sien-Sing Yang1, Wen-Chi Hou, Li-Wei Huang, Tzong-Huei Lee.
Abstract
A new C19 gamma-lactone, cinnakotolactone (1), along with a known analogue, isolinderanolide B (2), were isolated from the n-hexane layer of the leaf extracts of Cinnamomum kotoense. Their structures were elucidated on the basis of spectroscopic analysis. The anti-proliferation activities of 1 and 2 were evaluated against human HT29 and MCF-7 cancer cell lines, and their IC50 values ranged from 3.3 +/- 0.3 to 25.8 +/- 5.3 microM.Entities:
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Year: 2006 PMID： 17127517 DOI： 10.1080/14786410600906236
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861