Literature DB >> 17126599

Zinc homeostasis and immunity.

Lothar Rink1, Hajo Haase.   

Abstract

Zinc is an essential trace element for the immune system, and zinc deficiency compromises the function of primarily T cells but also of several other immune cells. Recently, zinc homeostasis has been demonstrated to affect dendritic cells, in particular the involvement of zinc transport proteins during lipopolysaccharide-induced upregulation of major histocompatibility complex proteins and co-stimulatory molecules. This adds to our understanding of the immunomodulatory potential of zinc and highlights its significance for immune function.

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Year:  2006        PMID： 17126599     DOI： 10.1016/j.it.2006.11.005

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  72 in total

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2.  Zinc supplementation increases zinc status and thymopoiesis in aged mice.

Authors:  Carmen P Wong; Yang Song; Valerie D Elias; Kathy R Magnusson; Emily Ho
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3.  Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.

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Review 4.  Mechanisms and regulation of the gene-expression response to sepsis.

Authors:  Timothy T Cornell; James Wynn; Thomas P Shanley; Derek S Wheeler; Hector R Wong
Journal:  Pediatrics       Date:  2010-05-17       Impact factor: 7.124

5.  Measuring zinc on the Roche cobas c502 analyzer-Validation, comparison, and pre-analytic aspects.

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6.  Intracellular accumulation dynamics and fate of zinc ions in alveolar epithelial cells exposed to airborne ZnO nanoparticles at the air-liquid interface.

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7.  Age-dependent signature of metallothionein expression in primary CD4 T cell responses is due to sustained zinc signaling.

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8.  Effects of zinc-fortified drinking skim milk (as functional food) on cytokine release and thymic hormone activity in very old persons: a pilot study.

Authors:  Laura Costarelli; Robertina Giacconi; Marco Malavolta; Andrea Basso; Francesco Piacenza; MariLuisa DeMartiis; Elvio Giannandrea; Carlo Renieri; Franco Busco; Roberta Galeazzi; Eugenio Mocchegiani
Journal:  Age (Dordr)       Date:  2014-04-26

9.  Alterations in early cytokine-mediated immune responses to Plasmodium falciparum infection in Tanzanian children with mineral element deficiencies: a cross-sectional survey.

Authors:  Erasto V Mbugi; Marjolein Meijerink; Jacobien Veenemans; Prescilla V Jeurink; Matthew McCall; Raimos M Olomi; John F Shao; Hans Verhoef; Huub Fj Savelkoul
Journal:  Malar J       Date:  2010-05-17       Impact factor: 2.979

10.  The immune system and the impact of zinc during aging.

Authors:  Hajo Haase; Lothar Rink
Journal:  Immun Ageing       Date:  2009-06-12       Impact factor: 6.400
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