| Literature DB >> 17126376 |
D Shcharbin1, M Szwedzka, M Bryszewska.
Abstract
The analysis of binding between cationic PAMAM G5 dendrimer and anionic fluorescent probe using fluorescence and equilibrium dialysis has been made. It was found that at low concentrations of ANS the double fluorimetric titration technique can be successfully used for quantitative analysis of binding of ANS to dendrimer. Based on fluorescence and dialysis data the constants of binding and the number of binding centers were calculated for binding of ANS to PAMAM G5 dendrimer: K(b) is approx. (0.5-1)x10(5)M(-1) and n is (0.5-0.7).Entities:
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Year: 2006 PMID： 17126376 DOI： 10.1016/j.bioorg.2006.10.003
Source DB: PubMed Journal: Bioorg Chem ISSN： 0045-2068 Impact factor: 5.275