| Literature DB >> 17126296 |
Ahmed M Korayem1, Thomas Hauling, Christine Lesch, Marco Fabbri, Malin Lindgren, Olga Loseva, Otto Schmidt, Mitchell S Dushay, Ulrich Theopold.
Abstract
Hemolymph coagulation stops bleeding and protects against infection. Clotting factors include both proteins that are conserved during evolution as well as more divergent proteins in different species. Here we show that several silk proteins also appear in the clot of the greater wax moth Galleria mellonella. RT-PCR analysis reveals that silk proteins are expressed in immune tissues and induced upon wounding in both Galleria and Ephestia kuehniella, a second pyralid moth. Our results support the idea that silk proteins were co-opted for immunity and coagulation during evolution.Entities:
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Year: 2006 PMID： 17126296 DOI： 10.1016/j.bbrc.2006.11.022
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575