BACKGROUND: Streptococcus agalactiae remains susceptible to penicillin; nevertheless, an increase in the resistance to other antimicrobial families, such as macrolides and more rarely fluoroquinolones, has been described. METHODS AND RESULTS: From 2003 to 2004, two fluoroquinolone-resistant S. agalactiae strains were detected. The strains presented one mutation in parC (Ser79 --> Phe) and an additional mutation in gyrA (Glu85 --> Ala or Glu85 --> Lys). CONCLUSION: This study describes the first S. agalactiae strains highly resistant to fluoroquinolones in Spain.
BACKGROUND:Streptococcus agalactiae remains susceptible to penicillin; nevertheless, an increase in the resistance to other antimicrobial families, such as macrolides and more rarely fluoroquinolones, has been described. METHODS AND RESULTS: From 2003 to 2004, two fluoroquinolone-resistant S. agalactiae strains were detected. The strains presented one mutation in parC (Ser79 --> Phe) and an additional mutation in gyrA (Glu85 --> Ala or Glu85 --> Lys). CONCLUSION: This study describes the first S. agalactiae strains highly resistant to fluoroquinolones in Spain.
Authors: G Piccinelli; F Gargiulo; S Corbellini; G Ravizzola; C Bonfanti; A Caruso; M A De Francesco Journal: Antimicrob Agents Chemother Date: 2015-02-09 Impact factor: 5.191