Literature DB >> 17125245

Acyl glucuronides: biological activity, chemical reactivity, and chemical synthesis.

Andrew V Stachulski1, John R Harding, John C Lindon, James L Maggs, B Kevin Park, Ian D Wilson.   

Abstract

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Year:  2006        PMID： 17125245     DOI： 10.1021/jm060599z

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  8 in total

1.  Discovery of N-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases.

Authors:  Hongjun Zhang; Blair T Lapointe; Neville Anthony; Rita Azevedo; Jos Cals; Craig C Correll; Matthew Daniels; Sujal Deshmukh; Hans van Eenenaam; Heidi Ferguson; Laxminarayan G Hegde; Willem Jan Karstens; John Maclean; J Richard Miller; Lily Y Moy; Vladimir Simov; Sunil Nagpal; Arthur Oubrie; Rachel L Palte; Gopal Parthasarathy; Nunzio Sciammetta; Mario van der Stelt; Janice D Woodhouse; B Wesley Trotter; Kenneth Barr
Journal:  ACS Med Chem Lett       Date:  2020-01-09       Impact factor: 4.345

2.  Mechanisms of Stereodirecting Participation and Ester Migration from Near and Far in Glycosylation and Related Reactions.

Authors:  Asiri A Hettikankanamalage; Robert Lassfolk; Filip S Ekholm; Reko Leino; David Crich
Journal:  Chem Rev       Date:  2020-07-05       Impact factor: 60.622

3.  Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients.

Authors:  Thomas G Hammond; Xiaoli Meng; Rosalind E Jenkins; James L Maggs; Anahi Santoyo Castelazo; Sophie L Regan; Stuart N L Bennett; Caroline J Earnshaw; Guruprasad P Aithal; Ira Pande; J Gerry Kenna; Andrew V Stachulski; B Kevin Park; Dominic P Williams
Journal:  J Pharmacol Exp Ther       Date:  2014-06-05       Impact factor: 4.030

4.  Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1.

Authors:  Robert L Dow; Jian-Cheng Li; Michael P Pence; E Michael Gibbs; Jennifer L LaPerle; John Litchfield; David W Piotrowski; Michael J Munchhof; Tara B Manion; William J Zavadoski; Gregory S Walker; R Kirk McPherson; Susan Tapley; Eliot Sugarman; Angel Guzman-Perez; Paul DaSilva-Jardine
Journal:  ACS Med Chem Lett       Date:  2011-03-18       Impact factor: 4.345

5.  In silico prediction of acyl glucuronide reactivity.

Authors:  Tim Potter; Richard Lewis; Tim Luker; Roger Bonnert; Michael A Bernstein; Timothy N Birkinshaw; Stephen Thom; Mark Wenlock; Stuart Paine
Journal:  J Comput Aided Mol Des       Date:  2011-10-26       Impact factor: 3.686

6.  The Application of Mass Spectrometry in Drug Metabolism and Pharmacokinetics.

Authors:  Ji-Yoon Lee; Sang Kyum Kim; Kiho Lee; Soo Jin Oh
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

7.  Identification of a novel glucuronyltransferase from Streptomyces chromofuscus ATCC 49982 for natural product glucuronidation.

Authors:  Jie Ren; Caleb Don Barton; Kathryn Eternity Sorenson; Jixun Zhan
Journal:  Appl Microbiol Biotechnol       Date:  2022-01-27       Impact factor: 4.813

8.  Acyl Group Migration in Pyranosides as Studied by Experimental and Computational Methods.

Authors:  Robert Lassfolk; Manuel Pedrón; Tomás Tejero; Pedro Merino; Johan Wärnå; Reko Leino
Journal:  Chemistry       Date:  2022-05-11       Impact factor: 5.020
  8 in total

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