Literature DB >> 17125231

C35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines.

Chin-Lin Hsieh1, Mei-Huims Tseng, Yi-Yuan Shao, Jang-Yang Chang, Ching-Chuan Kuo, Chi-Yen Chang, Yueh-Hsiung Kuo.   

Abstract

Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC50 values ranging from 11 to 14 microM.

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Year:  2006        PMID: 17125231     DOI: 10.1021/np0600550

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  2 in total

1.  Leaf Extracts of Calocedrus formosana (Florin) Induce G2/M Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells.

Authors:  Sheau-Yun Yuan; Chi-Chen Lin; Shih-Lan Hsu; Ya-Wen Cheng; Jyh-Horng Wu; Chen-Li Cheng; Chi-Rei Yang
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-12       Impact factor: 2.629

2.  PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.

Authors:  Ioannis Sainis; Katerina Vareli; Vasilios Karavasilis; Evangelos Briasoulis
Journal:  PPAR Res       Date:  2008       Impact factor: 4.964

  2 in total

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