Literature DB >> 17125227

Triterpene saponins from clematis mandshurica.

Shepo Shi1, Dan Jiang, Caixia Dong, Pengfei Tu.   

Abstract

Four new triterpene saponins, clematomandshurica saponins A-D (1-4), together with three known saponins (5-7) have been isolated from the roots and rhizomes of Clematis mandshurica. Their structures were elucidated on the basis of their spectroscopic evidence and hydrolysis. Clematomandshurica saponins A and B showed significant inhibitory activity on cyclooxygenase-2 (IC50 = 2.66 and 2.58 microM, respectively).

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Year:  2006        PMID： 17125227     DOI： 10.1021/np060287z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

1.  Saponin-rich fraction from Clematis chinensis Osbeck roots protects rabbit chondrocytes against nitric oxide-induced apoptosis via preventing mitochondria impairment and caspase-3 activation.

Authors:  Wenjun Wu; Xinghua Gao; Xianxiang Xu; Yubin Luo; Mei Liu; Yufeng Xia; Yue Dai
Journal:  Cytotechnology       Date:  2012-07-22       Impact factor: 2.058

2.  Inhibition of COX-2 and PGE2 in LPS-stimulated RAW264.7 cells by lonimacranthoide VI, a chlorogenic acid ester saponin.

Authors:  Fuqin Guan; Haiting Wang; Yu Shan; Yu Chen; Ming Wang; Qizhi Wang; Min Yin; Youyi Zhao; Xu Feng; Jianhua Zhang
Journal:  Biomed Rep       Date:  2014-07-11

3.  WIN-34B May Have Analgesic and Anti-Inflammatory Effects by Reducing the Production of Pro-Inflammatory Mediators in Cells via Inhibition of IκB Signaling Pathways.

Authors:  Kyoung Soo Kim; Hyun Mi Choi; Hyung-In Yang; Myung Chul Yoo
Journal:  Biomol Ther (Seoul)       Date:  2012-01       Impact factor: 4.634

4.  Development and validation of a chromatographic method for determining Clematichinenoside AR and related impurities.

Authors:  Yang Zhou; Yue Guan; Ji Shi; Xiaolin Zhang; Lan Yao; Lifang Liu
Journal:  Chem Cent J       Date:  2012-12-08       Impact factor: 4.215
  4 in total

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