Literature DB >> 17124130

Numerical modeling of the transport to an intravascular bubble in a tube with a soluble/insoluble surfactant.

Portonovo S Ayyaswamy1, Jie Zhang, David M Eckmann.   

Abstract

Using a newly developed algorithm in conjunction with the front tracking scheme, we have evaluated the transport associated with a deformable bubble moving in a tube in the presence of a soluble or an insoluble surfactant. Such evaluations are useful to the understanding of gas embolism--a common syndrome for decompression sickness. Decompression sickness may be encountered in performing extravehicular activity during space exploration. The numerical evaluations indicate that as the location of the adsorptive interface gets closer to the vessel wall, the surfactant amount on the wall gets depleted. The implication is that the process by which a bubble occluding a vessel dislodges may depend both on the strength of the diffusivity of the surfactant and the adsorption process. More detailed study is needed to clarify this observation. The numerical results evaluated include Marangoni flow, which causes a bubble to propel out of its initial static location, and bubble motion in Poiseuille flow. The presence of a soluble/insoluble surfactant slows down the bubble motion. For identical surface concentrations of the surfactant, the effect of the presence of a soluble surfactant is more severe on the retardation of the bubble motion than that of an insoluble surfactant.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17124130     DOI: 10.1196/annals.1362.042

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  1 in total

1.  Surfactant reduction of cerebral infarct size and behavioral deficit in a rat model of cerebrovascular arterial gas embolism.

Authors:  David M Eckmann; Stephen C Armstead
Journal:  J Appl Physiol (1985)       Date:  2013-07-11
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.