OBJECTIVES: This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome. MATERIALS AND METHODS: Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60-75% of peak heart rate (HRmax=194.5-[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC). RESULTS: When compared to baseline, MDA content was decreased significantly. CONCLUSION: Regular exercise significantly decreased lipoperoxidation in Down's syndrome.
OBJECTIVES: This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome. MATERIALS AND METHODS: Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60-75% of peak heart rate (HRmax=194.5-[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC). RESULTS: When compared to baseline, MDA content was decreased significantly. CONCLUSION: Regular exercise significantly decreased lipoperoxidation in Down's syndrome.
Authors: Jesmin Ara; Ailyn Fadriquela; Md Faruk Ahmed; Johny Bajgai; Ma Easter Joy Sajo; Sung Pyo Lee; Tae Su Kim; Jin Young Jung; Cheol Su Kim; Soo-Ki Kim; Kwang Yong Shim; Kyu-Jae Lee Journal: Biomed Res Int Date: 2018-04-18 Impact factor: 3.411