Literature DB >> 17121981

Preparation of monoclonal antibodies for detection and identification of Francisella tularensis.

Akitoyo Hotta1, Akihiko Uda, Osamu Fujita, Kiyoshi Tanabayashi, Akio Yamada.   

Abstract

Monoclonal antibodies (MAbs) against Francisella tularensis were obtained. Three MAbs specifically reacted with F. tularensis, while four MAbs reacted with other members of the genus Francisella as well. Fluorescent isothiocyanate-conjugated MAbs unequivocally stained bacterial cells in specimens from experimentally infected mice. Two MAbs agglutinated F. tularensis antigen in the agglutination tests. These MAbs should improve methods for detection and identification of F. tularensis.

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Year:  2006        PMID： 17121981      PMCID： PMC1797713          DOI： 10.1128/CVI.00057-06

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  21 in total

1.  Microagglutination test for early and specific serodiagnosis of tularemia.

Authors:  T Sato; H Fujita; Y Ohara; M Homma
Journal:  J Clin Microbiol       Date:  1990-10       Impact factor: 5.948

Review 2.  Tularemia: emergence/re-emergence.

Authors:  Jeannine M Petersen; Martin E Schriefer
Journal:  Vet Res       Date:  2005 May-Jun       Impact factor: 3.683

3.  A novel screening ELISA and a confirmatory Western blot useful for diagnosis and epidemiological studies of tularemia.

Authors:  P Schmitt; W Splettstösser; M Porsch-Ozcürümez; E J Finke; R Grunow
Journal:  Epidemiol Infect       Date:  2005-08       Impact factor: 2.451

4.  Mapping of immunoreactive antigens of Francisella tularensis live vaccine strain.

Authors:  Jana Havlasová; Lenka Hernychová; Petr Halada; Vera Pellantová; Jan Krejsek; Jirí Stulík; Ales Macela; Peter R Jungblut; Pär Larsson; Mats Forsman
Journal:  Proteomics       Date:  2002-07       Impact factor: 3.984

5.  Production and characterization of monoclonal antibodies directed against the lipopolysaccharide of Francisella tularensis.

Authors:  M J Fulop; T Webber; R J Manchee; D C Kelly
Journal:  J Clin Microbiol       Date:  1991-07       Impact factor: 5.948

6.  An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells.

Authors:  Igor Golovliov; Vladimir Baranov; Zuzana Krocova; Hana Kovarova; Anders Sjöstedt
Journal:  Infect Immun       Date:  2003-10       Impact factor: 3.441

Review 7.  Tularemia.

Authors:  Jill Ellis; Petra C F Oyston; Michael Green; Richard W Titball
Journal:  Clin Microbiol Rev       Date:  2002-10       Impact factor: 26.132

8.  Competitive enzyme immunoassay for antibodies to a 43,000-molecular-weight Francisella tularensis outer membrane protein for the diagnosis of tularemia.

Authors:  L Bevanger; J A Maeland; A I Naess
Journal:  J Clin Microbiol       Date:  1989-05       Impact factor: 5.948

9.  Immunogenicity and toxicity of lipopolysaccharide from Francisella tularensis LVS.

Authors:  G Sandström; A Sjöstedt; T Johansson; K Kuoppa; J C Williams
Journal:  FEMS Microbiol Immunol       Date:  1992-10

10.  Characterization of a novicida-like subspecies of Francisella tularensis isolated in Australia.

Authors:  Margaret J Whipp; Jennifer M Davis; Gary Lum; Jim de Boer; Yan Zhou; Scott W Bearden; Jeannine M Petersen; May C Chu; Geoff Hogg
Journal:  J Med Microbiol       Date:  2003-09       Impact factor: 2.472
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  4 in total

1.  Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide.

Authors:  Marly I Roche; Zhaohua Lu; Julia H Hui; Jacqueline Sharon
Journal:  Hybridoma (Larchmt)       Date:  2011-02

2.  Generation and characterization of hybridoma antibodies for immunotherapy of tularemia.

Authors:  Zhaohua Lu; Marly I Roche; Julia H Hui; Berkay Unal; Philip L Felgner; Sunita Gulati; Guillermo Madico; Jacqueline Sharon
Journal:  Immunol Lett       Date:  2007-08-08       Impact factor: 3.685

3.  Detection of Francisella tularensis-specific antibodies in patients with tularemia by a novel competitive enzyme-linked immunosorbent assay.

Authors:  Neekun Sharma; Akitoyo Hotta; Yoshie Yamamoto; Osamu Fujita; Akihiko Uda; Shigeru Morikawa; Akio Yamada; Kiyoshi Tanabayashi
Journal:  Clin Vaccine Immunol       Date:  2012-10-31

4.  The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.

Authors:  Zhaohua Lu; Michael J Rynkiewicz; Chiou-Ying Yang; Guillermo Madico; Hillary M Perkins; Qi Wang; Catherine E Costello; Joseph Zaia; Barbara A Seaton; Jacqueline Sharon
Journal:  Immunology       Date:  2013-11       Impact factor: 7.397
  4 in total

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