Literature DB >> 17121630

Antimicrobial prophylaxis to prevent surgical site infections in a rural sub-Saharan hospital.

J Fehr1, C Hatz, I Soka, P Kibatala, H Urassa, M Battegay, Z Jeffrey, T Smith, H Mshinda, R Frei, A F Widmer.   

Abstract

A prospective cohort study was performed to collect baseline data concerning surgical site infections (SSIs) and antimicrobial prophylaxis (AMP) in a remote sub-Saharan district hospital. The SSI rate of 22% was high. Most (88%) of the patients received prophylaxis after incision, and only 5% within the 30-min period before incision. Of all pathogens isolated from SSIs, 60% were resistant to the agent administered. The antibiotics given most frequently were chloramphenicol (60%), aminopenicillins (23%) and benzylpenicillin (15%). Staphylococcus aureus (36%), Escherichia coli (5%) and enterococci (4%) were the pathogens isolated most commonly from SSIs.

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Year:  2006        PMID: 17121630     DOI: 10.1111/j.1469-0691.2006.01551.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN: 1198-743X            Impact factor:   8.067


  13 in total

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2.  The Association Between Incorrect Use of Antibiotic Prophylaxis and in-Hospital Surgical Site Infections - A Prospective Observational Study.

Authors:  Gosaye Mekonen Tefera; Beshadu Bedada Feyisa; Getu Melesie Taye; Gurmu Tesfaye Umeta; Fekadu Negash Bereded; Hunduma Dinsa Ayeno; Diriba Alemayehu Gadisa; Tsegaye Melaku Kebede
Journal:  Infect Drug Resist       Date:  2020-09-07       Impact factor: 4.003

3.  Complications after intramedullary nailing of femoral fractures in a low-income country.

Authors:  Sven Young; Leonard N Banza; Geir Hallan; Fletcher Beniyasi; Kumbukani G Manda; Boston S Munthali; Eva Dybvik; Lars B Engesæter; Leif I Havelin
Journal:  Acta Orthop       Date:  2013-10-31       Impact factor: 3.717

4.  Assessment of surgical antimicrobial prophylaxis in Orthopaedics and Traumatology Surgical Unit of a Tertiary Care Teaching Hospital in Addis Ababa.

Authors:  Nitsuh Alemayehu Argaw; Kibruyisfawe Zewdie Shumbash; Alemseged Ayele Asfaw; Segewkal Hawaze
Journal:  BMC Res Notes       Date:  2017-04-20

5.  Antimicrobial use-related problems and their costs in surgery ward of Jimma University Medical Center: Prospective observational study.

Authors:  Gosaye Mekonen Tefera; Beshadu Bedada Feyisa; Tsegaye Melaku Kebede
Journal:  PLoS One       Date:  2019-05-17       Impact factor: 3.240

Review 6.  Surgical care in district hospitals in sub-Saharan Africa: a scoping review.

Authors:  Zineb Bentounsi; Sharaf Sheik-Ali; Grace Drury; Chris Lavy
Journal:  BMJ Open       Date:  2021-03-25       Impact factor: 2.692

Review 7.  Supporting global antimicrobial stewardship: antibiotic prophylaxis for the prevention of surgical site infection in low- and middle-income countries (LMICs): a scoping review and meta-analysis.

Authors:  Lesley Cooper; Jacqueline Sneddon; Daniel Kwame Afriyie; Israel A Sefah; Amanj Kurdi; Brian Godman; R Andrew Seaton
Journal:  JAC Antimicrob Resist       Date:  2020-10-05

8.  Predominance of multi-drug resistant bacterial pathogens causing surgical site infections in Muhimbili National Hospital, Tanzania.

Authors:  Joel Manyahi; Mecky I Matee; Mtebe Majigo; Sabrina Moyo; Stephen E Mshana; Eligius F Lyamuya
Journal:  BMC Res Notes       Date:  2014-08-07

9.  Nasal Carriage of Methicillin-Resistant Staphylococcus aureus among Health Care Workers in Tertiary and Regional Hospitals in Dar es Salam, Tanzania.

Authors:  Agricola Joachim; Sabrina J Moyo; Lillian Nkinda; Mtebe Majigo; Sima Rugarabamu; Elizabeth G Mkashabani; Elia J Mmbaga; Naboth Mbembati; Said Aboud; Eligius F Lyamuya
Journal:  Int J Microbiol       Date:  2018-09-10

10.  Bacterial Aetiology and Antibiotic Susceptibility Profile of Post-Operative Sepsis among Surgical Patients in a Tertiary Hospital in Rural Eastern Uganda.

Authors:  Masifa George; Jacob Stanley Iramiot; Rita Muhindo; Peter Olupot-Olupot; Ann Nanteza
Journal:  Microbiol Res J Int       Date:  2018-06-20
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