Literature DB >> 17121284

Antimalarial activity of concanamycin A alone and in combination with pyronaridine.

Saranya Auparakkitanon1, Prapon Wilairat.   

Abstract

Concanamycin A, a macrolide antibiotic inhibitor of vacuolar H+-ATPase derived from Streptomyces sp, inhibited Plasmodium falciparum K1 growth in culture with an IC500 value of 0.2 nM. It exhibited an additive effect when tested together with the antimalarial pyronaridine.

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Year:  2006        PMID： 17121284

Source DB:  PubMed          Journal:  Southeast Asian J Trop Med Public Health        ISSN： 0125-1562            Impact factor:   0.267


  3 in total

1.  Review of pyronaridine anti-malarial properties and product characteristics.

Authors:  Simon L Croft; Stephan Duparc; Sarah J Arbe-Barnes; J Carl Craft; Chang-Sik Shin; Lawrence Fleckenstein; Isabelle Borghini-Fuhrer; Han-Jong Rim
Journal:  Malar J       Date:  2012-08-09       Impact factor: 2.979

2.  Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.

Authors:  Shahul Hameed P; Suresh Solapure; Vikas Patil; Philipp P Henrich; Pamela A Magistrado; Sowmya Bharath; Kannan Murugan; Pavithra Viswanath; Jayashree Puttur; Abhishek Srivastava; Eknath Bellale; Vijender Panduga; Gajanan Shanbag; Disha Awasthy; Sudhir Landge; Sapna Morayya; Krishna Koushik; Ramanatha Saralaya; Anandkumar Raichurkar; Nikhil Rautela; Nilanjana Roy Choudhury; Anisha Ambady; Radha Nandishaiah; Jitendar Reddy; K R Prabhakar; Sreenivasaiah Menasinakai; Suresh Rudrapatna; Monalisa Chatterji; María Belén Jiménez-Díaz; María Santos Martínez; Laura María Sanz; Olivia Coburn-Flynn; David A Fidock; Amanda K Lukens; Dyann F Wirth; Balachandra Bandodkar; Kakoli Mukherjee; Robert E McLaughlin; David Waterson; Lyn Rosenbrier-Ribeiro; Kevin Hickling; V Balasubramanian; Peter Warner; Vinayak Hosagrahara; Adam Dudley; Pravin S Iyer; Shridhar Narayanan; Stefan Kavanagh; Vasan K Sambandamurthy
Journal:  Nat Commun       Date:  2015-03-31       Impact factor: 14.919

3.  Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box.

Authors:  Janette Reader; Mariëtte E van der Watt; Dale Taylor; Claire Le Manach; Nimisha Mittal; Sabine Ottilie; Anjo Theron; Phanankosi Moyo; Erica Erlank; Luisa Nardini; Nelius Venter; Sonja Lauterbach; Belinda Bezuidenhout; Andre Horatscheck; Ashleigh van Heerden; Natalie J Spillman; Anne N Cowell; Jessica Connacher; Daniel Opperman; Lindsey M Orchard; Manuel Llinás; Eva S Istvan; Daniel E Goldberg; Grant A Boyle; David Calvo; Dalu Mancama; Theresa L Coetzer; Elizabeth A Winzeler; James Duffy; Lizette L Koekemoer; Gregory Basarab; Kelly Chibale; Lyn-Marié Birkholtz
Journal:  Nat Commun       Date:  2021-01-11       Impact factor: 14.919
  3 in total

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