Literature DB >> 1711885

Study of immune function of cancer patients influenced by supplemental zinc or selenium-zinc combination.

W Mei1, Z M Dong, B L Liao, H B Xu.   

Abstract

Since hair Zn and serum Zn are usually decreased in cancer patients, and Zn deficiency may reduce the function of T-cells, granulocytes, and Nk cells, we observed in cancer patients the influences of the Zinc or Selenium-Zinc on DNCB skin delayed hypersensitivity mediated by T cell, and the effects of Zinc on oxidative metabolic function of neutrophils and level of serum interferon that potentiate NK cell activity. The results showed that DNCB skin reaction was strengthened, the oxidative metabolic function of neutrophils and serum interferon level were increased by the drugs. It is reasonable to expect that Zinc or Selenium-Zinc is instrumental in restoring failing immunocompetence of cancer patient.

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Year:  1991        PMID: 1711885     DOI: 10.1007/bf02990458

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  5 in total

1.  Induction of interferon-gamma in human leukocyte cultures stimulated by Zn2+.

Authors:  M Salas; H Kirchner
Journal:  Clin Immunol Immunopathol       Date:  1987-10

2.  Stimulation of the respiratory burst of murine peritoneal inflammatory neutrophils by conjugation with tumor cells.

Authors:  A Lichtenstein
Journal:  Cancer Res       Date:  1987-05-01       Impact factor: 12.701

3.  Phase II study of interferon alfa-2a, recombinant (Roferon-A) in metastatic renal cell carcinoma.

Authors:  A C Buzaid; A Robertone; C Kisala; S E Salmon
Journal:  J Clin Oncol       Date:  1987-07       Impact factor: 44.544

4.  Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma.

Authors:  J U Gutterman; G R Blumenschein; R Alexanian; H Y Yap; A U Buzdar; F Cabanillas; G N Hortobagyi; E M Hersh; S L Rasmussen; M Harmon; M Kramer; S Pestka
Journal:  Ann Intern Med       Date:  1980-09       Impact factor: 25.391

5.  Serum copper and zinc levels in melanoma patients.

Authors:  G L Fisher; L E Spitler; K L McNeill; L S Rosenblatt
Journal:  Cancer       Date:  1981-04-01       Impact factor: 6.860

  5 in total
  3 in total

1.  Effects of nutritional supplementation with selenium and zinc on natural killer cell activity in hemodialysis patients: a single-arm study.

Authors:  Haruki Sada; Akihiko Kato; Ryo Sumimoto; Hiromitsu Ohmori; Hideki Ohdan
Journal:  Int Urol Nephrol       Date:  2016-05-27       Impact factor: 2.370

2.  Mobility of human neutrophils in response to Cryptococcus neoformans cells, culture filtrate antigen, and individual components of the antigen.

Authors:  Z M Dong; J W Murphy
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

3.  Suppression of 9L gliosarcoma growth by copper depletion with copper-deficient diet and D-penicillamine.

Authors:  D Yoshida; Y Ikeda; S Nakazawa
Journal:  J Neurooncol       Date:  1993-08       Impact factor: 4.130

  3 in total

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