Rachel P Riechelmann1, Everardo D Saad. 1. Department of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto, Canada. Rachel.Riechelmann@uhn.on.ca
Abstract
OBJECTIVES: To systematically review drug interactions in oncology. METHODS: We searched PubMed for eligible articles and online databases abstracts of major oncology meetings from 2002 to 2005. RESULTS: One study reported on the frequency of drug interactions. Interactions between chemotherapy and nonchemotherapy agents have been reported mostly in small clinical trials and case series. Interactions between chemotherapic agents have been reported mostly in Phase I studies. Few studies described fatal outcomes of drug interactions in cancer patients. CONCLUSION: Drug interactions comprise an important issue in oncology, but very limited data exist on their frequency and clinical consequences.
OBJECTIVES: To systematically review drug interactions in oncology. METHODS: We searched PubMed for eligible articles and online databases abstracts of major oncology meetings from 2002 to 2005. RESULTS: One study reported on the frequency of drug interactions. Interactions between chemotherapy and nonchemotherapy agents have been reported mostly in small clinical trials and case series. Interactions between chemotherapic agents have been reported mostly in Phase I studies. Few studies described fatal outcomes of drug interactions in cancerpatients. CONCLUSION: Drug interactions comprise an important issue in oncology, but very limited data exist on their frequency and clinical consequences.
Authors: Arti Hurria; Ilene S Browner; Harvey Jay Cohen; Crystal S Denlinger; Mollie deShazo; Martine Extermann; Apar Kishor P Ganti; Jimmie C Holland; Holly M Holmes; Mohana B Karlekar; Nancy L Keating; June McKoy; Bruno C Medeiros; Ewa Mrozek; Tracey O'Connor; Stephen H Petersdorf; Hope S Rugo; Rebecca A Silliman; William P Tew; Louise C Walter; Alva B Weir; Tanya Wildes Journal: J Natl Compr Canc Netw Date: 2012-02 Impact factor: 11.908
Authors: M Angeles Fernández de Palencia Espinosa; M Sacramento Díaz Carrasco; José Luis Fuster Soler; Guadalupe Ruíz Merino; M Amelia De la Rubia Nieto; Alberto Espuny Miró Journal: Int J Clin Pharm Date: 2014-09-10