Literature DB >> 1711764

Immunomodulators interfere with angiopathy but not vasospasm after subarachnoid haemorrhage in rabbits.

M Ryba1, K Iwańska, M Walski, M Pastuszko.   

Abstract

The present study deals with the effects of immunomodulators on the morphology of intracerebral arterial walls in rabbits with experimental subarachnoid haemorrhage (SAH). Immunostimulators:thymostimuline and inosine dimethylamino-isopropanol-p-acetamido-benzoate were found to aggravate the angiopathic changes, whereas immunosuppressive drugs-cyclosporine A and azathioprine appeared to prevent the damage. The authors consider the possibility of using immunosuppressive drugs in patients with ruptured intracranial aneurysms.

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Year:  1991        PMID： 1711764     DOI： 10.1007/bf01407672

Source DB:  PubMed          Journal:  Acta Neurochir (Wien)        ISSN： 0001-6268            Impact factor:   2.216


  14 in total

1.  Angiographic evidence of basilar artery constriction in the rabbit: a new model of vasospasm.

Authors:  K F Baker; N T Zervas; J Pile-Spellman; F X Vacanti; D Miller
Journal:  Surg Neurol       Date:  1987-02

2.  [Immunological study of late cerebral vasospasm in subarachnoid hemorrhage. Detection of immunoglobulins, C3, and fibrinogen in cerebral arterial walls by immunofluorescence method].

Authors:  T Hoshi; T Shimizu; K Kito; N Yamasaki; K Takahashi; M Takahashi; T Okada; H Kasuya; K Kitamura
Journal:  Neurol Med Chir (Tokyo)       Date:  1984-09       Impact factor: 1.742

3.  Response of chronic experimental cerebral vasospasm to methylprednisolone and dexamethasone.

Authors:  D Chyatte; T M Sundt
Journal:  J Neurosurg       Date:  1984-05       Impact factor: 5.115

4.  Delayed cerebral vasospasm is not reversible by aminophylline, nifedipine, or papaverine in a "two-hemorrhage" canine model.

Authors:  V G Varsos; T M Liszczak; D H Han; J P Kistler; J Vielma; P M Black; R C Heros; N T Zervas
Journal:  J Neurosurg       Date:  1983-01       Impact factor: 5.115

5.  Immune complexes in peripheral blood polymorphonuclear leucocytes of patients with Raynaud's phenomenon.

Authors:  J van der Maulen; A A Wouda; E Mandema; T H The
Journal:  Clin Exp Immunol       Date:  1979-01       Impact factor: 4.330

6.  Immune complexes and complement activation following rupture of intracranial saccular aneurysms.

Authors:  J R Ostergaard; B O Kristensen; S E Svehag; B Teisner; T Miletic
Journal:  J Neurosurg       Date:  1987-06       Impact factor: 5.115

7.  Is the vasospasm following subarachnoidal hemorrhage an immunoreactive disease?

Authors:  L Pellettieri; C A Carlson; L Lindholm
Journal:  Experientia       Date:  1981-11-15

8.  The angiopathy of subarachnoid hemorrhage: angiographic and morphologic correlates.

Authors:  R R Smith; B R Clower; D F Peeler; J Yoshioka
Journal:  Stroke       Date:  1983 Mar-Apr       Impact factor: 7.914

9.  Experimental vasospasm: experiences with a canine model and failure of naloxone therapy.

Authors:  A Sakaguchi; G J Dohrmann; S Mojtahedi
Journal:  Surg Neurol       Date:  1984-11

10.  Cerebral artery spasm. A histological study at necropsy of the blood vessels in cases of subarachnoid hemorrhage.

Authors:  J T Hughes; P M Schianchi
Journal:  J Neurosurg       Date:  1978-04       Impact factor: 5.115
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  6 in total

1.  Expression of intercellular adhesion molecule 1 (ICAM-1) on the cerebral artery following subarachnoid haemorrhage in rats.

Authors:  Y Handa; T Kubota; M Kaneko; A Tsuchida; H Kobayashi; H Kawano; T Kubota
Journal:  Acta Neurochir (Wien)       Date:  1995       Impact factor: 2.216

2.  2-Chloro-2' deoxyadenosine prevents angiopathic changes in cerebral arteries in experimental SAH in rabbits.

Authors:  M Ryba; P Grieb; M Walski; J Sawicki; M Pastuszko
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

3.  Is vascular angiopathy following intracranial aneurysm rupture immunologically mediated?

Authors:  M Ryba; M Jarzabek-Chorzelska; T Chorzelski; M Pastuszko
Journal:  Acta Neurochir (Wien)       Date:  1992       Impact factor: 2.216

4.  A strategy for analyzing multiple parameters with application to aneurysmal SAH patients all of them clipped but treated with and without cyclosporine.

Authors:  M Ryba; M Pastuszko; C Dziewiecki; J Andrychowski; P Bojarski; M Barczewska
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

5.  Impaired in vitro proliferative response of suppressor lymphocytes in patients with subarachnoid haemorrhage from ruptured intracranial aneurysm.

Authors:  M Ryba; P Grieb; M Pastuszko; B Wegier-Filipiuk; E Mrowiec; J Andrychowski; L Konopka
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216

6.  Successful prevention of neurological deficit in SAH patients with 2-chlorodeoxyadenosine.

Authors:  M Ryba; P Grieb; M Pastuszko; J Bidziński; J Andrychowski; C Dziewiecki; P Bojarski; L Królicki
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216
  6 in total

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