Literature DB >> 1711761

Hereditary diabetes insipidus: an immunohistochemical study of the hypothalamus and pituitary gland.

C Bergeron1, K Kovacs, C Ezrin, C Mizzen.   

Abstract

We report the histological findings in a case of hereditary diabetes insipidus (HDI) using vasopressin (VP) immunohistochemistry. The hypothalamus displayed a marked loss of magnocellular VP neurons, with preservation of the smaller cells. The neurohypophysis was severely atrophic with scanty immunoreactivity. Our results support the hypothesis that HDI results from a selective degeneration of VP neurons affecting chiefly the magnocellular elements projecting to the neurohypophysis. The sparing of the parvocellular component may reflect the projection of these neurons to non-pituitary targets.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1711761     DOI： 10.1007/bf00305879

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  7 in total

1.  A QUANTITATIVE EVALUATION OF HYPOTHALAMIC DEGENERATION AND ITS RELATION TO DIABETES INSIPIDUS FOLLOWING INTERRUPTION OF THE HUMAN HYPOPHYSEAL STALK.

Authors:  D A MACCUBBIN; J M VANBUREN
Journal:  Brain       Date:  1963-09       Impact factor: 13.501

2.  HEREDITARY IDIOPATHIC DIABETES INSIPIDUS. A CASE REPORT WITH AUTOPSY FINDINGS.

Authors:  L E BRAVERMAN; J P MANCINI; D M MCGOLDRICK
Journal:  Ann Intern Med       Date:  1965-09       Impact factor: 25.391

3.  Primary or idiopathic diabetes insipidus: a system disease.

Authors:  H BLOTNER
Journal:  Metabolism       Date:  1958-05       Impact factor: 8.694

4.  Immunocytochemical localization of the vasopressinergic and the oxytocinergic neurons in the human hypothalamus.

Authors:  K Dierickx; F Vandesande
Journal:  Cell Tissue Res       Date:  1977-10-21       Impact factor: 5.249

5.  A quantitative analysis of the normal neuron population of the hypothalamic magnocellular nuclei in man and of their projections to the neurohypophysis.

Authors:  A Morton
Journal:  J Comp Neurol       Date:  1969-06       Impact factor: 3.215

6.  Heredtary and idiopathic types of diabetes insipidus.

Authors:  J R Green; G C Buchan; E C Alvord; A G Swanson
Journal:  Brain       Date:  1967-09       Impact factor: 13.501

7.  Identification of parvocellular vasopressin and neurophysin neurons in the suprachiasmatic nucleus of a variety of mammals including primates.

Authors:  M V Sofroniew; A Weindl
Journal:  J Comp Neurol       Date:  1980-10-01       Impact factor: 3.215
  7 in total
  13 in total

1.  Clinical and molecular analysis of a Chinese family with autosomal dominant neurohypophyseal diabetes insipidus associated with a novel missense mutation in the vasopressin-neurophysin II gene.

Authors:  Yongfeng Luo; Binbin Wang; Yu Qiu; Chuan Zhang; Chengluo Jin; Yakun Zhao; Qingguo Zhu; Xu Ma
Journal:  Endocrine       Date:  2012-02-04       Impact factor: 3.633

2.  Molecular basis of autosomal dominant neurohypophyseal diabetes insipidus. Cellular toxicity caused by the accumulation of mutant vasopressin precursors within the endoplasmic reticulum.

Authors:  M Ito; J L Jameson; M Ito
Journal:  J Clin Invest       Date:  1997-04-15       Impact factor: 14.808

3.  AVP-NPII gene mutations and clinical characteristics of the patients with autosomal dominant familial central diabetes insipidus.

Authors:  Doga Turkkahraman; Emel Saglar; Tugce Karaduman; Hatice Mergen
Journal:  Pituitary       Date:  2015-12       Impact factor: 4.107

4.  A novel variation in the AVP gene resulting in familial neurohypophyseal diabetes insipidus in a large Italian kindred.

Authors:  Camilla Birkegaard; Jane H Christensen; Alberto Falorni; Stefania Marzotti; Viviana Minarelli; Niels Gregersen; Søren Rittig
Journal:  Pituitary       Date:  2013-06       Impact factor: 4.107

Review 5.  Development of the human hypothalamus.

Authors:  D F Swaab
Journal:  Neurochem Res       Date:  1995-05       Impact factor: 3.996

6.  A murine model of autosomal dominant neurohypophyseal diabetes insipidus reveals progressive loss of vasopressin-producing neurons.

Authors:  Theron A Russell; Masafumi Ito; Mika Ito; Richard N Yu; Fred A Martinson; Jeffrey Weiss; J Larry Jameson
Journal:  J Clin Invest       Date:  2003-12       Impact factor: 14.808

Review 7.  Functional neuroanatomy and neuropathology of the human hypothalamus.

Authors:  D F Swaab; M A Hofman; P J Lucassen; J S Purba; F C Raadsheer; J A Van de Nes
Journal:  Anat Embryol (Berl)       Date:  1993-04

8.  Familial neurohypophyseal diabetes insipidus: clinical, genetic and functional studies of novel mutations in the arginine vasopressin gene.

Authors:  Maria Inês Alvelos; Ângela Francisco; Leonor Gomes; Isabel Paiva; Miguel Melo; Pedro Marques; Susana Gama-de-Sousa; Sofia Carreiro; Telma Quintela; Isabel Gonçalves; Manuel Carlos Lemos
Journal:  Pituitary       Date:  2021-01-12       Impact factor: 4.107

9.  Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders.

Authors:  K Macdonald; D Feifel
Journal:  Front Neurosci       Date:  2013-03-15       Impact factor: 4.677

10.  Apoptosis of supraoptic AVP neurons is involved in the development of central diabetes insipidus after hypophysectomy in rats.

Authors:  Yihua Wang; Cuiping Zhao; Zhigang Wang; Chengwei Wang; Wenfeng Feng; Lijin Huang; Jialin Zhang; Songtao Qi
Journal:  BMC Neurosci       Date:  2008-06-25       Impact factor: 3.288
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.