Literature DB >> 1711731

Cardiac myxomas: immunohistochemical study of benign and malignant variants.

E Curschellas1, D Toia, M Borner, M J Mihatsch, F Gudat.   

Abstract

Immunohistochemical investigation of 11 cardiac myxomas (CMs) including one malignant metastasizing CM showed a co-expression of epithelial (lu-5 and CAM 5.2), mesenchymal (vimentin) and neuroendocrine antigens (neuron-specific enolase) in all tumour cells. Factor VIII was found in the endothelial cells of capillaries only. In the subendocardium of fetal heart tissue close to the foramen ovale myofibroblasts reacting with the panepithelial antibody lu-5 were detected. We conclude that CMs are neoplasms that may develop from embryonic cell remnants.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1711731     DOI： 10.1007/bf01606497

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histopathol        ISSN： 0174-7398


  22 in total

1.  The development of cardiac myxomas and papillary endocardial lesions from mural thrombus.

Authors:  W R Salyer; D L Page; G M Hutchins
Journal:  Am Heart J       Date:  1975-01       Impact factor: 4.749

Review 2.  Cardiac hormones. I. Review on the morphology, biochemistry, and molecular biology of the endocrine heart.

Authors:  W G Forssmann
Journal:  Eur J Clin Invest       Date:  1986-12       Impact factor: 4.686

3.  Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Authors:  S M Hsu; L Raine; H Fanger
Journal:  J Histochem Cytochem       Date:  1981-04       Impact factor: 2.479

4.  [Clinical findings, diagnosis and pathology of heart-tumors with special reference to myxoma (author's transl)].

Authors:  A Moser; F Follath; E Grädel; M J Mihatsch; H E Schmitt
Journal:  Schweiz Rundsch Med Prax       Date:  1978-08-29

Review 5.  Histogenesis of cardiac myxomas. An immunohistochemical study of 19 cases, including one with glandular structures, and review of the literature.

Authors:  L Johansson
Journal:  Arch Pathol Lab Med       Date:  1989-07       Impact factor: 5.534

6.  Heterogeneous expression of factor VIII/von Willebrand factor by cardiac myxoma cells.

Authors:  R D McComb
Journal:  Am J Surg Pathol       Date:  1984-07       Impact factor: 6.394

7.  Cardiac myxomas. An immunohistochemical study using endothelial, histiocytic, and smooth-muscle cell markers.

Authors:  G Landon; N G Ordóñez; L A Guarda
Journal:  Arch Pathol Lab Med       Date:  1986-02       Impact factor: 5.534

8.  Cardiac myxoma: an immunoperoxidase study of histogenesis.

Authors:  M E Boxer
Journal:  Histopathology       Date:  1984-09       Impact factor: 5.087

9.  Metastasizing atrial myxoma.

Authors:  I S Seo; T F Warner; R A Colyer; R F Winkler
Journal:  Am J Surg Pathol       Date:  1980-08       Impact factor: 6.394

10.  Glandular cardiac myxomas. Histologic, immunohistochemical, and ultrastructural evidence of epithelial differentiation.

Authors:  B I Goldman; C Frydman; N Harpaz; S F Ryan; D Loiterman
Journal:  Cancer       Date:  1987-05-15       Impact factor: 6.860
View more
  2 in total

1.  Cytokeratin profile and neuroendocrine cells in the glandular component of cardiac myxoma.

Authors:  Angela Pucci; Giovanni Bartoloni; Elena Tessitore; J Aidan Carney; Mauro Papotti
Journal:  Virchows Arch       Date:  2003-09-13       Impact factor: 4.064

Review 2.  Molecular basis of cardiac myxomas.

Authors:  Pooja Singhal; Adriana Luk; Vivek Rao; Jagdish Butany
Journal:  Int J Mol Sci       Date:  2014-01-20       Impact factor: 5.923
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.