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Literature DB >> 17117159

Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity.

Alicia B Berger, Kelly B Sexton, Matthew Bogyo.

Abstract

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Year: 2006 PMID： 17117159 DOI： 10.1038/sj.cr.7310112

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

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37 in total

Review 1. Allosteric regulation of protease activity by small molecules.

Authors: Aimee Shen
Journal: Mol Biosyst Date: 2010-06-10

2. Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB.

Authors: Aaron W Puri; Patrick J Lupardus; Edgar Deu; Victoria E Albrow; K Christopher Garcia; Matthew Bogyo; Aimee Shen
Journal: Chem Biol Date: 2010-11-24

Review 3. Human caspases: activation, specificity, and regulation.

Authors: Cristina Pop; Guy S Salvesen
Journal: J Biol Chem Date: 2009-05-26 Impact factor: 5.157

4. A Nanopore Approach for Analysis of Caspase-7 Activity in Cell Lysates.

Authors: Bach Pham; Scott J Eron; Maureen E Hill; Xin Li; Monifa A Fahie; Jeanne A Hardy; Min Chen
Journal: Biophys J Date: 2019-08-02 Impact factor: 4.033

5. Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes.

Authors: D V Delfino; S Spinicelli; N Pozzesi; S Pierangeli; E Velardi; S Bruscoli; M P Martelli; V Pettirossi; L Falchi; T-b Kang; C Riccardi
Journal: Cell Death Differ Date: 2010-07-30 Impact factor: 15.828

6. Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling.

Authors: Vasanthy Vigneswara; Nsikan Akpan; Martin Berry; Ann Logan; Carol M Troy; Zubair Ahmed
Journal: Brain Date: 2014-04-10 Impact factor: 13.501

Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity.

Review 1. Allosteric regulation of protease activity by small molecules.

2. Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB.

Review 3. Human caspases: activation, specificity, and regulation.

4. A Nanopore Approach for Analysis of Caspase-7 Activity in Cell Lysates.

5. Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes.

6. Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling.

Review 7. Small Molecule Active Site Directed Tools for Studying Human Caspases.

8. Caspase selective reagents for diagnosing apoptotic mechanisms.

9. Mechanism of pyrethroid pesticide-induced apoptosis: role of calpain and the ER stress pathway.

10. Mind bomb 1 regulation of cFLIP interactions.