| Literature DB >> 17116487 |
Rumana Rashid1, Roderick J Johnson, Stephen Morris, Helen Dickinson, Jarek Czyz, Sheila J M O'Connor, Roger G Owen.
Abstract
Chromosome analysis of a patient with intravascular large B-cell lymphoma (IVL) revealed a complex, near-tetraploid karyotype with 83 chromosomes. Abnormalities included a t(11;14)(q13;q32), which was confirmed with both interphase fluorescence in situ hybridization (FISH) using an IGH/cyclin D1 dual-color, dual-fusion probe set and cyclin D1 immunohistochemical analysis. Abnormality of 3q was also evident. Interphase FISH analysis with a dual-color, break-apart probe set confirmed rearrangement of BCL6. To our knowledge, this is the first report of these abnormalities in IVL.Entities:
Mesh：
Substances：
Year: 2006 PMID： 17116487 DOI： 10.1016/j.cancergencyto.2006.07.018
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608