Literature DB >> 17116040

Mesial temporal inhibition in a patient with deep brain stimulation of the anterior thalamus for epilepsy.

Dominik Zumsteg1, Andres M Lozano, Richard A Wennberg.   

Abstract

We investigated the electrophysiological effects of high-frequency anterior thalamic deep brain stimulation using intracerebral mesial and lateral temporal depth electrodes in a patient with intractable focal epilepsy. Monopolar and bipolar stimulation delivered to the thalamic anterior nucleus using the programmable ITREL II stimulation device led to a significant decrease of cross power spectral density and a nonsignificant decrease of coherence in ipsilateral hippocampal structures. No such effect was found in lateral temporal or contralateral sites. The hippocampal inhibition was clearly related to the voltage (> or =7 V) and frequency (> or =70 Hz) of the thalamic stimulus and occurred with a delay of approximately 60 s after stimulus onset.

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Year:  2006        PMID： 17116040     DOI： 10.1111/j.1528-1167.2006.00824.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN： 0013-9580            Impact factor:   5.864


  21 in total

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10.  Brain areas controlling heart rate variability in tinnitus and tinnitus-related distress.

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