Literature DB >> 17114983

Therapeutic hypothermia after cardiac arrest: unintentional overcooling is common using ice packs and conventional cooling blankets.

Raina M Merchant1, Benjamin S Abella, Mary Ann Peberdy, Jasmeet Soar, Marcus E H Ong, Gregory A Schmidt, Lance B Becker, Terry L Vanden Hoek.   

Abstract

OBJECTIVES: Although therapeutic hypothermia for cardiac arrest survivors has been shown to improve neurologically intact survival, optimal methods to ensure controlled induction and maintenance of cooling are not clearly established. Precise temperature control is important to evaluate because unintentional overcooling below the consensus target range of 32-34 degrees C may place the patient at risk for serious complications. We sought to measure the prevalence of overcooling (<32 degrees C) in postarrest survivors receiving primarily noninvasive cooling.
DESIGN: Retrospective chart review of postarrest patients.
SETTING: Three large teaching hospitals. PATIENTS: Cardiac arrest survivors receiving therapeutic hypothermia.
INTERVENTIONS: Charts were reviewed if primarily surface cooling was used with a target temperature goal between 32 degrees C and 34 degrees C.
MEASUREMENTS AND MAIN RESULTS: Of the 32 cases reviewed, overcooling lasting for >1 hr was identified as follows: 20 of 32 patients (63%) reached temperatures of <32 degrees C, 9 of 32 (28%) reached temperatures of <31 degrees C, and 4 of 32 (13%) reached temperatures of <30 degrees C. Of those with overcooling of <32 degrees C, 6 of 20 (30%) survived to hospital discharge, whereas of those without overcooling, 7 of 12 (58%) survived to hospital discharge (p = not significant).
CONCLUSIONS: The majority of the cases reviewed demonstrated unintentional overcooling below target temperature. Improved mechanisms for temperature control are required to prevent potentially deleterious complications of more profound hypothermia.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17114983     DOI: 10.1097/01.CCM.0000246016.28679.36

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  38 in total

Review 1.  Cardiopulmonary resuscitation and management of cardiac arrest.

Authors:  Jerry P Nolan; Jasmeet Soar; Volker Wenzel; Peter Paal
Journal:  Nat Rev Cardiol       Date:  2012-06-05       Impact factor: 32.419

Review 2.  Therapeutic hypothermia for acute neurological injuries.

Authors:  Lucia Rivera-Lara; Jiaying Zhang; Susanne Muehlschlegel
Journal:  Neurotherapeutics       Date:  2012-01       Impact factor: 7.620

3.  [Therapeutic hypothermia after cardiopulmonary resuscitation - pro and con].

Authors:  Christoph Pechlaner; Michael Joannidis
Journal:  Wien Med Wochenschr       Date:  2008

Review 4.  Therapeutic hypothermia for cardiac arrest: a practical approach.

Authors:  David B Seder; Salam Jarrah
Journal:  Curr Neurol Neurosci Rep       Date:  2008-11       Impact factor: 5.081

5.  Strategies for therapeutic hypometabothermia.

Authors:  Shimin Liu; Jiang-Fan Chen
Journal:  J Exp Stroke Transl Med       Date:  2012-01-01

6.  Induced hypothermia as a neuroprotectant in post-cardiac arrest.

Authors:  Mohi E Alkadri; Paul McMullan
Journal:  Ochsner J       Date:  2009

7.  Therapeutic hypothermia after cardiac arrest: performance characteristics and safety of surface cooling with or without endovascular cooling.

Authors:  Alexander C Flint; J Claude Hemphill; David C Bonovich
Journal:  Neurocrit Care       Date:  2007       Impact factor: 3.210

8.  Active surface cooling protocol to induce mild therapeutic hypothermia after out-of-hospital cardiac arrest: a retrospective before-and-after comparison in a single hospital.

Authors:  Creighton W Don; W T Longstreth; Charles Maynard; Michele Olsufka; Graham Nichol; Todd Ray; Nicole Kupchik; Steven Deem; Michael K Copass; Leonard A Cobb; Francis Kim
Journal:  Crit Care Med       Date:  2009-12       Impact factor: 7.598

9.  Therapeutic hypothermia for cardiac arrest: a practical approach.

Authors:  David B Seder; Salam Jarrah
Journal:  Curr Treat Options Neurol       Date:  2009-03       Impact factor: 3.598

10.  A tertiary care center's experience with therapeutic hypothermia after pediatric cardiac arrest.

Authors:  Ericka L Fink; Robert S B Clark; Patrick M Kochanek; Michael J Bell; R Scott Watson
Journal:  Pediatr Crit Care Med       Date:  2010-01       Impact factor: 3.624

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.