Literature DB >> 17113992

Targeting lipoxygenases with care.

Patricia M de Souza1, Justine Newson, Derek W Gilroy.   

Abstract

Though fish oils possess cardio-protective, anti-inflammatory, and anti-cancer properties, their molecular and biochemical mechanism of action is lacking. In this issue of Chemistry & Biology, Tjonahen and colleagues identify a new metabolite of eicosapentanoic acid, resolvin E2, produced by 5-lipoxygenase.

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Year:  2006        PMID: 17113992     DOI: 10.1016/j.chembiol.2006.11.002

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  2 in total

1.  Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation.

Authors:  Sungwhan F Oh; Padmini S Pillai; Antonio Recchiuti; Rong Yang; Charles N Serhan
Journal:  J Clin Invest       Date:  2011-01-04       Impact factor: 14.808

Review 2.  Paradigm shift - Metabolic transformation of docosahexaenoic and eicosapentaenoic acids to bioactives exemplify the promise of fatty acid drug discovery.

Authors:  Ganesh V Halade; Laurence M Black; Mahendra Kumar Verma
Journal:  Biotechnol Adv       Date:  2018-02-28       Impact factor: 14.227

  2 in total

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