Literature DB >> 1711373

Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.

G Tzimagiorgis1, N K Moschonas.   

Abstract

We isolated and analysed a full-length mouse brain glutamate dehydrogenase (GLUD) cDNA as a preliminary step to use the mouse model for the investigation of GLUD function in neurotransmission and neurodegeneration. GLUD coding sequences were found highly conserved among mouse, human and rat. Northern blots revealed two transcripts with different ratios in different mouse organs implying some mechanism of tissue-specific expression. In contrast to human, mouse GLUD gene family appears not to contain an intronless member.

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Year:  1991        PMID： 1711373     DOI： 10.1016/0167-4781(91)90017-g

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  6 in total

1.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-10-25       Impact factor: 16.971

2.  Evolution of glutamate dehydrogenase genes: evidence for two paralogous protein families and unusual branching patterns of the archaebacteria in the universal tree of life.

Authors:  N Benachenhou-Lahfa; P Forterre; B Labedan
Journal:  J Mol Evol       Date:  1993-04       Impact factor: 2.395

3.  3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes.

Authors:  S Wang; J H Nadeau; A Duncan; M F Robert; G Fontaine; K Schappert; K R Johnson; E Zietkiewicz; P Hruz; H Miziorko
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

4.  Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability.

Authors:  Xiaodong Bao; Ranu Pal; Kevin N Hascup; Yongfu Wang; Wen-Tung Wang; Wenhao Xu; Dongwei Hui; Abdulbaki Agbas; Xinkun Wang; Mary L Michaelis; In-Young Choi; Andrei B Belousov; Greg A Gerhardt; Elias K Michaelis
Journal:  J Neurosci       Date:  2009-11-04       Impact factor: 6.167

5.  A membrane-bound form of glutamate dehydrogenase possesses an ATP-dependent high-affinity microtubule-binding activity.

Authors:  F Rajas; B Rousset
Journal:  Biochem J       Date:  1993-10-15       Impact factor: 3.857

6.  The NADP-glutamate dehydrogenase of the cyanobacterium Synechocystis 6803: cloning, transcriptional analysis and disruption of the gdhA gene.

Authors:  S Chávez; J C Reyes; F Chauvat; F J Florencio; P Candau
Journal:  Plant Mol Biol       Date:  1995-04       Impact factor: 4.076
  6 in total

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