Literature DB >> 17112961

The use of a segmented transducer for rib sparing in HIFU treatments.

John Civale1, Robert Clarke, Ian Rivens, Gail ter Haar.   

Abstract

The use of focused ultrasound as a minimally invasive treatment for tumours is rapidly expanding. Target organs include the liver and kidneys. Both single element and phased array transducers may be used in the clinic. The presence of the rib cage presents a problem in high intensity focused ultrasound (HIFU) treatment planning, due to its high attenuation of the HIFU beam resulting in a loss of power at the focus as well as an increase in the risk of damage at the rib and to overlying tissues, including the skin. In this paper, a linearly segmented transducer, in which all active elements are driven in phase, has been investigated. The aim of the study was to investigate how a beam with a clinically useful profile could be achieved by removing the contribution of edge segments from one side of the transducer to the field. We have considered the case in which the HIFU beam approaches the rib cage during a treatment and investigated configurations of the transducer for which up to three segments on the edge are switched off. This problem has been studied initially using a linear acoustic field program to model the segmented transducer's acoustic beam profile. Experimental measurements of the transducer's acoustic field were performed using an automated beam plotting system. Temperature measurements were made on a rib surface for two transducer configurations using a fine wire thermocouple. A thermochromic liquid crystal material was used to assess qualitatively the heating pattern generated by the ultrasound beam. We show the rib sparing potential of the segmented transducer during HIFU treatment by demonstrating a reduction in the prefocal width of the ultrasound beam when edge segments are switched off. This has been predicted with the acoustic field model and demonstrated experimentally by acoustic field measurements and observations of the heating pattern generated by the ultrasound beam. A significant decrease in the temperature rise on a rib was observed in the case for which three edge segments were switched off compared with when all segments were active. We conclude that a segmented transducer extends the potential for treating liver tumours. In the case where the tumour lies behind, but close to the edge of, the ribs, energy loss at the focus and excessive heating in the rib and overlying tissue can be avoided by switching off edge segments.

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Year:  2006        PMID: 17112961     DOI: 10.1016/j.ultrasmedbio.2006.06.005

Source DB:  PubMed          Journal:  Ultrasound Med Biol        ISSN: 0301-5629            Impact factor:   2.998


  17 in total

1.  Transcostal high-intensity-focused ultrasound: ex vivo adaptive focusing feasibility study.

Authors:  J-F Aubry; M Pernot; F Marquet; M Tanter; M Fink
Journal:  Phys Med Biol       Date:  2008-05-12       Impact factor: 3.609

Review 2.  Focused ultrasound surgery in oncology: overview and principles.

Authors:  Clare M C Tempany; Nathan J McDannold; Kullervo Hynynen; Ferenc A Jolesz
Journal:  Radiology       Date:  2011-04       Impact factor: 11.105

Review 3.  Image-guided ultrasound phased arrays are a disruptive technology for non-invasive therapy.

Authors:  Kullervo Hynynen; Ryan M Jones
Journal:  Phys Med Biol       Date:  2016-08-05       Impact factor: 3.609

4.  Focused ultrasound transducer spatial peak intensity estimation: a comparison of methods.

Authors:  John Civale; Ian Rivens; Adam Shaw; Gail Ter Haar
Journal:  Phys Med Biol       Date:  2018-03-07       Impact factor: 3.609

5.  Lesion generation through ribs using histotripsy therapy without aberration correction.

Authors:  Yohan Kim; Tzu-Yin Wang; Zhen Xu; Charles A Cain
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2011-11       Impact factor: 2.725

6.  HIFU Power Monitoring Using Combined Instantaneous Current and Voltage Measurement.

Authors:  Chris Adams; James R McLaughlan; Thomas M Carpenter; Steven Freear
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2019-09-12       Impact factor: 2.725

7.  Blocked Elements in 1-D and 2-D Arrays-Part II: Compensation Methods as Applied to Large Coherent Apertures.

Authors:  Marko Jakovljevic; Nick Bottenus; Lily Kuo; Shalki Kumar; Jeremy J Dahl; Gregg E Trahey
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2017-03-16       Impact factor: 2.725

8.  Focusing of high-intensity ultrasound through the rib cage using a therapeutic random phased array.

Authors:  Svetlana Bobkova; Leonid Gavrilov; Vera Khokhlova; Adam Shaw; Jeffrey Hand
Journal:  Ultrasound Med Biol       Date:  2010-06       Impact factor: 2.998

9.  The role of acoustic nonlinearity in tissue heating behind a rib cage using a high-intensity focused ultrasound phased array.

Authors:  Petr V Yuldashev; Svetlana M Shmeleva; Sergey A Ilyin; Oleg A Sapozhnikov; Leonid R Gavrilov; Vera A Khokhlova
Journal:  Phys Med Biol       Date:  2013-03-26       Impact factor: 3.609

10.  HIFU Drive System Miniaturization Using Harmonic Reduced Pulsewidth Modulation.

Authors:  Chris Adams; Thomas M Carpenter; David Cowell; Steven Freear; James R McLaughlan
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2018-10-29       Impact factor: 2.725

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