Literature DB >> 17110696

MR spectroscopy in sinus mucocele: N-acetyl mimics of brain N-acetylaspartate.

E Andre1, M Xu, D Yang, J K Siow, T T Yeo, Y Xu, C C T Lim.   

Abstract

We describe MR spectroscopy in 2 patients with frontal sinus mucoceles that showed a dominant metabolite peak at 2.0-ppm chemical shift, simulating N-acetylaspartate (NAA) of normal neuronal tissue. In vitro analysis of postsurgical mucocele samples confirmed that the signal at 2.0 ppm was arising from the methyl moiety of an N-acetyl compound. This is probably caused by N-acetylgalactosamine or N-acetylglucosamine, which are glycoproteins found in normal respiratory mucus produced by the paranasal sinus epithelium.

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Year:  2006        PMID: 17110696      PMCID: PMC7977234     

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  9 in total

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Journal:  Biochemistry       Date:  1994-12-20       Impact factor: 3.162

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  9 in total
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  7 in total

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