Literature DB >> 1710816

The lipopolysaccharide of Shigella bacteria as a virulence factor.

A A Lindberg1, A Kärnell, A Weintraub.   

Abstract

The virulence factors of the lipopolysaccharide of Shigella species bacteria include the endotoxic activities of the lipid A component of the molecule and the ability of the polysaccharide chain--the core and the O-antigenic polysaccharide--to provide the bacterium with resistance to host defense mechanisms such as opsonization, phagocytosis, and intracellular killing. Structural features of the lipopolysaccharides of four Shigella species-S. dysenteriae, S. flexneri, S. boydii, and S. sonnei--are described.

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Year:  1991        PMID: 1710816     DOI: 10.1093/clinids/13.supplement_4.s279

Source DB:  PubMed          Journal:  Rev Infect Dis        ISSN: 0162-0886


  33 in total

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4.  Highly homogenous tri-acylated S-LPS acts as a novel clinically applicable vaccine against Shigella flexneri 2a infection.

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Review 5.  Vaccines against human diarrheal pathogens: current status and perspectives.

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8.  O-specific [corrected] polysaccharide conjugate vaccine-induced [corrected] antibodies prevent invasion of Shigella into Caco-2 cells and may be curative.

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Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-07       Impact factor: 11.205

Review 9.  Pathogenicity islands in bacterial pathogenesis.

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Journal:  Clin Microbiol Rev       Date:  2004-01       Impact factor: 26.132

10.  Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody.

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