Literature DB >> 17106483

The First Synthesis of a Diynone from Echinacea pallida.

George A Kraus1, Jaehoon Bae, Jessica Schuster.   

Abstract

In order to provide an authentic standard and to generate pure material for biological testing, an efficient synthetic route to 1 was developed. This represents the first total synthesis of a major bioactive diynone from E. pallida.

Entities:  

Year:  2005        PMID： 17106483      PMCID： PMC1615886          DOI： 10.1055/s-2005-918418

Source DB:  PubMed          Journal:  Synthesis (Stuttg)        ISSN： 0039-7881            Impact factor:   3.157


  3 in total

1.  Light-mediated antifungal activity of Echinacea extracts.

Authors:  S E Binns; B Purgina; C Bergeron; M L Smith; L Ball; B R Baum; J T Arnason
Journal:  Planta Med       Date:  2000-04       Impact factor: 3.352

2.  TLC and HPLC Analysis of Alkamides in Echinacea Drugs1,2.

Authors:  R Bauer; P Remiger
Journal:  Planta Med       Date:  1989-08       Impact factor: 3.352

3.  Straightforward synthesis of panaxytriol: an active component of Red Ginseng.

Authors:  Heedong Yun; Samuel J Danishefsky
Journal:  J Org Chem       Date:  2003-05-30       Impact factor: 4.354
  3 in total
  4 in total

1.  The synthesis and natural distribution of the major ketone constituents in Echinacea pallida.

Authors:  George A Kraus; Jaehoon Bae; Lankun Wu; Eve Wurtele
Journal:  Molecules       Date:  2007-03-10       Impact factor: 4.411

2.  Echinacea increases arginase activity and has anti-inflammatory properties in RAW 264.7 macrophage cells, indicative of alternative macrophage activation.

Authors:  Zili Zhai; Avery Solco; Lankun Wu; Eve S Wurtele; Marian L Kohut; Patricia A Murphy; Joan E Cunnick
Journal:  J Ethnopharmacol       Date:  2008-12-07       Impact factor: 4.360

3.  Cytokine- and interferon-modulating properties of Echinacea spp. root tinctures stored at -20 degrees C for 2 years.

Authors:  Dustin A McCann; Avery Solco; Yi Liu; Filippo Macaluso; Patricia A Murphy; Marian L Kohut; David S Senchina
Journal:  J Interferon Cytokine Res       Date:  2007-05       Impact factor: 2.607

4.  Quinones as key intermediates in natural products Synthesis. Syntheses of bioactive xanthones from Hypericum perforatum.

Authors:  George A Kraus; John Mengwasser
Journal:  Molecules       Date:  2009-08-03       Impact factor: 4.411
  4 in total

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